Original Article
25 May 2014 / 17 April 2024 by almaware
Background: Natural rubber latex allergy is a condition at high risk of anaphylaxis during surgery. However, latex contains several protein allergens and not all of them may show the same clinical relevance. Objective: To investigate the clinical relevance of Hev b 8, the natural rubber latex profilin. Methods: Seven patients without a clinical history of […]
Read more »
Background: Lipid transfer protein (LTP) is a widely cross-reacting plant pan-allergen, and sensitized patients may react to many foods. Although peanut allergy is frequently reported by LTP-allergic patients, the evidence of the presence of an allergen homologous to LTP in peanuts is limited. Objective: To assess the prevalence of peanut allergy in patients sensitized to […]
20 May 2014 / 17 April 2024 by almaware
Background: Very few studies have evaluated the effects of sublingual immunotherapy (SLIT) in elderly adults with either rhinitis or bronchial asthma. The aim of this study was to ascertain whether SLIT is effective in these patients. Methods: One hundred and sixty seven patients (aged 18-65 years) with persistent rhinitis and mild asthma, selected from 573 […]
The natural history of respiratory allergy is commonly characterized by a worsening of symptom severity, frequent comorbidity of rhinitis and asthma, and polysensitization to aeroallergens. The polysensitization phenomenon starts since childhood and is rare to find monosensitized adult patients. However, there are few studies investigating the characteristics of polysensitized patients. Methods: This study was performed […]
Background: Statins are serum cholesterol-lowering agents used for the prevention and treatment of atherosclerotic vascular disease. There is, however, growing evidence that statins have immunomodulatory and anti-inflammatory activities and may prove invaluable in the treatment of immunological and inflammatory disorders. Objective: On these basis we evaluated the effect of statins on the proliferation of fibroblasts […]
Celiac disease (CD) is a chronic inflammatory enteropathy of the small bowel resulting from a local TH1-mediated reaction to wheat gliadins and barley, rye and oat prolamins with the development of auto-antibodies to transglutaminases. As well as for other chronic inflammatory diseases, genetic background and environmental factors participate to pathogenesis. An increased traffic of CD34+ […]
Background: Fruits and vegetables may contain both labile and stable allergens. The former induce only OAS, whereas stable allergens may induce systemic reactions. Component- resolved diagnosis (CRD) of allergy to plant foods is therefore essential for the clinical management of allergic patients. Methods: 80 adults allergic to plant foods underwent SPT with purified natural date […]
Objective of the Study: The aim of our work is to ascertain the frequency and the impact of acute allergic reactions on the routine of a highly-specialized Emergency Department collecting information on the admission, the typology of symptoms and the degree of severity calculating the incidence and the outcomes of the events. Materials and methods: […]
Background. Overweight and obesity are major health issues in Western societies. They are related with a higher risk of different co-morbidities but their relationship with airway hyperresponsiveness (AHR) is still under discussion. Nevertheless, they are related to higher severity in asthma and other respiratory diseases. The aim of the study was to analyze the AHR […]
Background: Nocebo effect is the occurrence of troublesome symptoms after the administration of inert substances. It can be easily studied during blind oral challenges for drug reactions, which always involve the administration of a placebo. Methods: We collected data about nocebo effect in outpatients undergoing oral drug challenge. Patients with previous documented adverse reactions to […]