Original Article
12 May 2025 by edra | Leave a Comment
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus affecting mainly young individuals with a high burden of comorbid atopic diseases and is associated with increased morbidity. Proton pump inhibitors (PPIs) is often the first line of treatment by inducing clinical remission in 30-50% of patients. Recently new drugs, such as budesonide orodispersible […]
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9 May 2025 / 14 May 2025 by edra | Leave a Comment
Background. Allergy is a multifactorial disease in which variant genetic and environmental factors are involved. Pathophysiology of food allergy (FA) and its natural history are poorly understood till now. Novel biomarkers and curative treatment options are strongly required. We aimed to study the significance of serum sphingosine 1 phosphate (S1P) level in food allergy and […]
29 April 2025 by edra | Leave a Comment
Background. Data on epidemiology of anaphylaxis are difficult to record. During the lockdown in 2020-2021 due to Coronavirus disease 2019 (COVID-19), referrals to Emergency Department (E.D.) reduced. The aims of the study are to determine anaphylaxis frequency before and during COVID-19 pandemic and risk factors for severity. Methods. Clinical records from a general E.D. of […]
Background. Diagnostic criteria for hypereosinophilia (HE) have been revised. Accordingly, the minimum interval between the two results with an absolute eosinophil count (AEC) ≥ 1500 cells/µL has been reduced from 4 to 2 weeks. The aims of this study were to identify patients with HE according to the new diagnostic criteria in children and demonstrate […]
Background. Understanding the reason for the decrease in atopic dermatitis risk in preterm patients may be crucial for the development of prophylaxis and therapeutic measures. The hypotheses include a change in T-helper1/T-helper2/T-helper17 balance, thymus development, and intestinal colonization. This study was designed to compare these parameters between preterm and term patients. Methods. The investigated population […]
29 April 2025 / 29 April 2025 by edra | Leave a Comment
Background. Many physicians believe delivering medications for asthma exacerbation via nebulizers is more efficacious than using a metered dose inhaler (MDI) with spacer. This study aimed to evaluate pediatricians and allergists’ chosen method in children under 5 years: MDI with spacer or nebulizer. Methods. A brief survey was sent via electronic mail to a randomly […]
28 April 2025 / 28 April 2025 by edra | Leave a Comment
Background. The aim of this study is to translate and validate the Italian Version of the Anaphylaxis Quality of Life Scale for Adults (A-QoL-Adults), made up of the three subscales Social impact (SQoL), Emotional impact (EQol) and Limitations on Life (LoL) to measure the impact of the risk of anaphylaxis from any cause on patients’ […]
Background. Platinum compounds (PC) and taxanes (TX) are drugs frequently administered for the treatment of several cancers. In recent years, their increased use has been accompanied by a relatively high prevalence of hypersensitivity reactions (HSRs). In this study, we report our comprehensive experience of allergy skin test (ST) evaluation in 276 patients who experienced HSRs […]
28 April 2025 / 13 May 2025 by edra | Leave a Comment
Background. Hen’s egg allergy is one of the most common pediatric food allergies, requiring accurate diagnosis and management strategies. Oral food challenges (OFCs) are critical in evaluating food allergies; however, limited research has focused on the outcomes of challenges involving egg yolks. This retrospective study aims to assess the outcomes and characteristics of pediatric patients […]
24 April 2025 / 24 April 2025 by edra | Leave a Comment
Background. Mosquitoes are a family of the order Diptera. Throughout the world, there are two groups able to suck human blood and transmit diseases: the anophelines and the culicines comprise several genera such as Culex, Aedes and Aedes communis (Ac). Previous study has demostrated a significant relationship between Ac sensitization and either extract or single […]