Original Article
25 June 2026 / 25 June 2026 by edra
Background. Recent advancements in hereditary angioedema (HAE) management have focused mainly on long-term prophylaxis (LTP), aiming to achieve total disease control and normalize patients’ lives. The latest international guidelines recommend as first-line options for LTP plasma-derived C1-INH, lanadelumab, and berotralstat. Berotralstat is a highly selective inhibitor of plasma kallikrein and the first licensed oral therapy […]
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Background. Eosinophilic esophagitis (EoE) is a chronic, immune-mediated esophageal disorder that has been increasingly recognized over recent decades. It is characterized by a type 2 inflammatory response, shared with other type 2 inflammatory conditions such as allergic rhinitis (AR), food allergy (FA), atopic dermatitis (AD), bronchial asthma (BA), and chronic rhinosinusitis with nasal polyps (CRSwNP). […]
Review
25 June 2026 / 2 July 2026 by edra
Background. Lipid transfer protein (LTP)–mediated food allergy represents one of the most severe and heterogeneous forms of IgE-mediated food allergy in Mediterranean populations. Although Pru p 3 is the main marker of LTP sensitization, the clinical relevance of pollen-derived LTPs such as Art v 3 remains incompletely defined. Methods. We conducted a retrospective observational study […]
10 June 2026 / 10 June 2026 by edra
Background. Permanent tattoos introduce pigments and metal contaminants into the dermis, potentially triggering allergic contact dermatitis (ACD). However, comparative analyses between tattooed and non-tattooed individuals remain limited. This study aimed to assess the impact of tattoos on allergic sensitization and patch test (PT) reactivity. Methods. Retrospective observational analysis of 485 adults undergoing PT at two […]
10 June 2026 / 1 July 2026 by edra
Background. Eosinophilia in hospitalized patients is associated with increased mortality. However, eosinophilia was poorly investigated in the intensive care unit (ICU). The aim of our study was to investigate the prevalence of eosinophilia and its association with clinical outcomes in critically ill patients. Methods. This retrospective cohort study analyzed data from the Russian Intensive Care […]