Commentary
20 May 2026 / 20 May 2026 by edra
Comment on “Clinical terminology and biological mediators in allergology: why biomarkers do not define a syndrome” – doi: 10.23822/EurAnnACI.1764-1489.437
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Letter to the Editor
20 May 2026 by edra
Original Article
Background. Obesity is associated with worse asthma outcomes, partly due to inflammasome-mediated neutrophilic Type IVc immunity. However, the impact of adiposity on Type IVb airway inflammation remains poorly understood. This study aimed to evaluate the effect of body fat on Type 2 (T2) airway inflammation, measured using fractional exhaled nitric oxide (FeNO). Methods. This community-based […]
20 May 2026 / 21 May 2026 by edra
23 March 2026 / 23 March 2026 by edra
Background. Cross-reactivity among phylogenetically distant invertebrates—such as mites, crustaceans, and mollusks—is mainly driven by conserved panallergens including tropomyosin, arginine kinase, and troponin C. However, the clinical impact and molecular basis of these cross-reactivities remain incompletely defined. Methods. A multicenter observational study was conducted in 3,777 patients reactive to at least one arthropod or invertebrate allergen […]
20 March 2026 / 23 March 2026 by edra
Background. The allergic asthma phenotype is the most extensively investigated. However, few studies have explored the association between sensitization to different aeroallergens, asthma severity and blood eosinophil counts, an important biomarker of Type 2 inflammation. This study aims to evaluate associations between sensitization to aeroallergens, severity of asthma, eosinophilic phenotypes and age of onset of […]
20 March 2026 / 20 March 2026 by edra
Background. Tree nut and peanut allergy are common, and often persistent conditions, that significantly affect quality of life. Multiple nut avoidance is common due to cross-reactivity concerns but may cause unnecessary restrictions. Data regarding multiple nut oral food challenges (MN-OFC) remains limited. Our aim was to evaluate the safety and clinical impact of MN-OFC in […]
18 March 2026 / 18 March 2026 by edra
Review
13 March 2026 / 18 March 2026 by edra
Long-lived plasma cells (LLPCs) constitute a specialized and durable arm of humoral memory. While their role in maintaining long-term IgG and IgA immunity is firmly established, their contribution to IgE-mediated allergic disease remains clinically unproven. Nevertheless, recent advances in LLPC biology—accelerated substantially since 2021—have shown that IgE⁺ LLPC-like cells do exist in human bone marrow […]