Original Article
20 October 2026 by edra
Background. Growing evidence suggests that cross-reactivity between penicillins and cephalosporins is mainly driven by R1 side-chain similarity rather than the beta-lactam core. Although cefuroxime, ceftriaxone and cefixime appear to have a low cross-reactivity risk, their use in patients with confirmed penicillin hypersensitivity (HS) remains inconsistent. We aimed to assess the prevalence of HS to cephalosporins […]
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Background. Chronic spontaneous urticaria (CSU) is a common, challenging condition, usually impairs patients’ quality of life. While current medications are mainly symptom-based, many people still suffer. There is limited and inconclusive evidence suggesting a possible role of gluten sensitivity in CSU, and current international guidelines do not recommend a gluten-free diet as a standard therapeutic […]
Letter to the Editor
19 October 2026 by edra
Background. Multiplex diagnostics may identify IgE reactivity without a corresponding phenotype documented at testing. This record-level discordance can reflect incomplete history, limited exposure, cross-recognition, or broader atopy and is not equivalent to asymptomatic sensitisation. We described concordance across six allergen groups and routine-care reassessment of selected Pru p 3/nsLTP and Hymenoptera findings. Methods. We retrospectively […]
Commentary Correspondence
1 October 2026 / 19 October 2026 by edra
29 September 2026 / 19 October 2026 by edra
Background. Skin testing is a cornerstone of the diagnostic work-up of Hymenoptera venom allergy. However, evidence comparing high-concentration venom prick testing (Soluprick 300 μg/mL) with others skin prick testing (SPT) and intradermal testing (IDT) remains limited. Methods. In this multicenter retrospective study, 123 consecutive adult patients evaluated for Hymenoptera venom allergy at three tertiary allergy […]
25 September 2026 / 19 October 2026 by edra
25 September 2026 by edra
Background. Food allergy (FA) is a growing public health concern among school-aged children. Schools are high-risk settings for accidental exposures and anaphylaxis, yet staff frequently report insufficient preparedness to manage such emergencies. Educational programs are essential to improve knowledge, confidence, and preventive practices. This study aimed to develop and evaluate a nationwide web-based FA training […]