Letter to the Editor
18 March 2026 / 18 March 2026 by edra
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Review
13 March 2026 / 18 March 2026 by edra
Long-lived plasma cells (LLPCs) constitute a specialized and durable arm of humoral memory. While their role in maintaining long-term IgG and IgA immunity is firmly established, their contribution to IgE-mediated allergic disease remains clinically unproven. Nevertheless, recent advances in LLPC biology—accelerated substantially since 2021—have shown that IgE⁺ LLPC-like cells do exist in human bone marrow […]
Original Article
13 March 2026 / 13 March 2026 by edra
Background. Flaxseed allergy is a rare and potentially underdiagnosed condition. In recent years, sensitization to flaxseed has increased due to its growing presence in the human diet. This study presents three distinct cases of flaxseed allergy and discusses the strengths and limitations of current diagnostic tools in identifying this emerging allergy. Methods. Each case underwent […]
12 March 2026 / 13 March 2026 by edra
Background. Anaphylaxis is the most severe form of acute systemic allergic reactions. Several recommendations have been proposed to guide and standardize anaphylaxis approach and management. The objective of this study is to characterize a cohort of patients referred through an anaphylaxis fast-track system, to enhance and standardize anaphylaxis patient care. Methods. Observational study including patients […]
12 March 2026 by edra
Background. Hereditary angioedema (HAE) is a rare genetic disorder with variable prevalence, characterized by recurrent swelling in various parts of the body, including potential laryngeal attacks, significantly affecting patients’ quality of life. Methods. A nationwide, cross-sectional survey study was conducted between December 2023 and June 2024, targeting adults (aged 18 and older). The patients filled […]
Background. The diagnosis of immediate drug allergy (DA) relies on a combination of skin tests (ST), drug provocation tests (DPT), specific IgE levels (sIgE) and/or basophil activation tests (BAT). We aimed to compare BAT results with those of other allergy tests in patients with suspected immediate DA to a heterogeneous group of drugs, aiming to […]
12 March 2026 / 12 March 2026 by edra
16 January 2026 / 16 January 2026 by edra
Background. Oral immunotherapy (OIT) is a promising strategy for severe and persistent cow’s milk (CM) allergy. However, clinical experience concerning long-term follow-up is scarce. The objective is to assess long-term efficacy and safety of maintenance phase of OIT in real-life. Methods. Prospective study of children with severe IgE-mediated CM allergy that underwent CM-OIT, and were […]
15 January 2026 / 15 January 2026 by edra
Background. Soy allergy represents a diagnostic challenge, particularly when mediated by Gly m 4, a PR-10 protein known for its cross-reactivity with birch pollen allergens. Traditional diagnostic methods, including skin prick tests (SPTs) and specific IgE assays, often lack sensitivity or specificity, especially for Gly m 4-mediated allergies. Methods. In this study, the basophil activation […]