Original Article
20 October 2026 by edra
Background. Growing evidence suggests that cross-reactivity between penicillins and cephalosporins is mainly driven by R1 side-chain similarity rather than the beta-lactam core. Although cefuroxime, ceftriaxone and cefixime appear to have a low cross-reactivity risk, their use in patients with confirmed penicillin hypersensitivity (HS) remains inconsistent. We aimed to assess the prevalence of HS to cephalosporins […]
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Background. Chronic spontaneous urticaria (CSU) is a common, challenging condition, usually impairs patients’ quality of life. While current medications are mainly symptom-based, many people still suffer. There is limited and inconclusive evidence suggesting a possible role of gluten sensitivity in CSU, and current international guidelines do not recommend a gluten-free diet as a standard therapeutic […]
Letter to the Editor
19 October 2026 by edra
Background. Multiplex diagnostics may identify IgE reactivity without a corresponding phenotype documented at testing. This record-level discordance can reflect incomplete history, limited exposure, cross-recognition, or broader atopy and is not equivalent to asymptomatic sensitisation. We described concordance across six allergen groups and routine-care reassessment of selected Pru p 3/nsLTP and Hymenoptera findings. Methods. We retrospectively […]
Commentary Correspondence
1 October 2026 / 19 October 2026 by edra