Original Article
2 July 2025 by edra
HAE is a rare disease manifesting with recurrent attacks of disabling and potentially life-threatening angioedema for which early diagnosis and effective therapy are critical. Recent scientific progress and the development of novel therapeutic options has engendered multiple important changes in the diagnosis and management of the disease. In an attempt to encourage and facilitate the […]
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2 July 2025 / 2 July 2025 by edra
Background. Mixed rhinitis (MR) is a potential diagnosis for patients with allergic rhinitis (AR) who present symptoms following exposure to allergens yet also exhibit a significant burden of symptoms after exposure to non-specific irritants. MR is thought to be more prevalent than the isolated form of the disease (AR). However, there are still no established […]
12 May 2025 by edra
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus affecting mainly young individuals with a high burden of comorbid atopic diseases and is associated with increased morbidity. Proton pump inhibitors (PPIs) is often the first line of treatment by inducing clinical remission in 30-50% of patients. Recently new drugs, such as budesonide orodispersible […]
9 May 2025 / 14 May 2025 by edra
Background. Allergy is a multifactorial disease in which variant genetic and environmental factors are involved. Pathophysiology of food allergy (FA) and its natural history are poorly understood till now. Novel biomarkers and curative treatment options are strongly required. We aimed to study the significance of serum sphingosine 1 phosphate (S1P) level in food allergy and […]
29 April 2025 by edra
Background. Data on epidemiology of anaphylaxis are difficult to record. During the lockdown in 2020-2021 due to Coronavirus disease 2019 (COVID-19), referrals to Emergency Department (E.D.) reduced. The aims of the study are to determine anaphylaxis frequency before and during COVID-19 pandemic and risk factors for severity. Methods. Clinical records from a general E.D. of […]
Background. Diagnostic criteria for hypereosinophilia (HE) have been revised. Accordingly, the minimum interval between the two results with an absolute eosinophil count (AEC) ≥ 1500 cells/µL has been reduced from 4 to 2 weeks. The aims of this study were to identify patients with HE according to the new diagnostic criteria in children and demonstrate […]
Background. Understanding the reason for the decrease in atopic dermatitis risk in preterm patients may be crucial for the development of prophylaxis and therapeutic measures. The hypotheses include a change in T-helper1/T-helper2/T-helper17 balance, thymus development, and intestinal colonization. This study was designed to compare these parameters between preterm and term patients. Methods. The investigated population […]
29 April 2025 / 29 April 2025 by edra
Background. Many physicians believe delivering medications for asthma exacerbation via nebulizers is more efficacious than using a metered dose inhaler (MDI) with spacer. This study aimed to evaluate pediatricians and allergists’ chosen method in children under 5 years: MDI with spacer or nebulizer. Methods. A brief survey was sent via electronic mail to a randomly […]
28 April 2025 / 28 April 2025 by edra
Background. The aim of this study is to translate and validate the Italian Version of the Anaphylaxis Quality of Life Scale for Adults (A-QoL-Adults), made up of the three subscales Social impact (SQoL), Emotional impact (EQol) and Limitations on Life (LoL) to measure the impact of the risk of anaphylaxis from any cause on patients’ […]
Background. Platinum compounds (PC) and taxanes (TX) are drugs frequently administered for the treatment of several cancers. In recent years, their increased use has been accompanied by a relatively high prevalence of hypersensitivity reactions (HSRs). In this study, we report our comprehensive experience of allergy skin test (ST) evaluation in 276 patients who experienced HSRs […]