Original Article
16 May 2014 / 17 April 2024 by almaware
Background. Allergic rhinitis and asthma may be associated, bronchial hyperreactivity (BHR) is quite common in AR patients. It has been reported that allergen bronchial challenge induces nasal inflammation.Methacholine (MCH) is a stimulus able to elicit BHR.There is no study that investigated the effect ofMCH bronchial challenge on the nose.Objective. The aim of this study was […]
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Background: The cross-reactive allergen responsible for the so called “mugwort-celeryspice-syndrome”, a pollen-food allergy that occurs in a minority of mugwort pollen-allergic patients, is still undefined.Objective: To identify the allergen responsible for the cross-reactivity between mugwort pollen and plant-derived foods. Methods: The serum from one index patient with both fennel and mugwort pollen allergy was used […]
Background. Specific immunotherapy (SIT) efficacy and safety by subcutaneous (SCIT) and sublingual (SLIT) route is supported by literature data. Pre-coseasonal treatment is currently the more accepted option for pollen immunotherapy in terms of costs and patient’s compliance. This retrospective study evaluated the patient’s preference concerning subcutaneous or sublingual route in pre-coseasonal treatment.Materials andmethods.We evaluated 145 […]
In recent years there has been increasing prevalence of allergic diseases globally, especially in children.Many IgE-dependent allergic manifestations have been described in HIV-infected individuals. However, it seems to be controversial whether immunological changes, such as IgE elevation, results from the infection or is related to the presence of allergy in these subjects. The aim of […]
Background:The prevalence of IgE reactivity against genuine walnut and hazelnut allergens is poorly defined. Objective: The IgE response to walnut and hazelnut was investigated in Italian patients with primary allergy to these nuts. Methods: Sera from 36 patients allergic to hazelnut and/or walnut, not reactive to PR-10, profilin, and LTP, underwent immunoblot analysis with extracts […]
Background: Allergic rhinoconjunctivitis is a clinical condition that impairs quality of life.The use of traditional drugs in many cases is not enough to improve quality of life in these patients. Methods: In this pilot study we used the Sanispira Nasal filters in 15 patients (mean age 34,7 years) affected by allergic rhinoconjunctivitis for 18 days. […]
Background and Objective. Single SLIT studies with native allergen extracts support a dose-response effect for clinical and immunological outcomes. Conversely for carbamylated allergoids this dose-response effects is less evident, likely because the threshold for efficacy is more easily reached through the enhanced bioavailability of the extract consequent to the selective chemical modification. Thus this pilot […]
15 May 2014 / 17 April 2024 by almaware
Background: Food is one of the leading causes of anaphylaxis. In the Netherlands, patients visit a general practitioner (GP) as often as an emergency department (ED) in case of an acute food allergic reaction. So far, the management of food allergic reactions by GPs has not been investigated. Therefore, we explored the management of acute […]
9 May 2014 / 17 April 2024 by almaware
Component resolved diagnosis (CRD) represents an innovative and revolutionary tool in allergy diagnosis. At the same time, some criticisms can be outlined. The present web survey aimed at investigating the role of CRD in daily clinical practice, according to a sample of Italian specialists who manage allergic patients. 127 physicians, mostly allergists, completed the questionnaire, […]
Usually, hyperresponsiveness to inhaled methacholine is considered closely associated with a diagnosis of bronchial asthma. Recently, it has been clearly pointed out that bronchial hyperreactivity (BHR) is not a constant feature of asthma and that this condition is not always related to airways inflammation.In the present study we evaluated 42 Patients (21 positive and 21 […]