Original Article
20 May 2014 / 17 April 2024 by almaware
The natural history of respiratory allergy is commonly characterized by a worsening of symptom severity, frequent comorbidity of rhinitis and asthma, and polysensitization to aeroallergens. The polysensitization phenomenon starts since childhood and is rare to find monosensitized adult patients. However, there are few studies investigating the characteristics of polysensitized patients. Methods: This study was performed […]
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Background: Statins are serum cholesterol-lowering agents used for the prevention and treatment of atherosclerotic vascular disease. There is, however, growing evidence that statins have immunomodulatory and anti-inflammatory activities and may prove invaluable in the treatment of immunological and inflammatory disorders. Objective: On these basis we evaluated the effect of statins on the proliferation of fibroblasts […]
16 May 2014 / 17 April 2024 by almaware
Introduction. Although the efficacy and safety of high dose hypoallergenic mite subcutaneous immunotherapy (SCIT) using a conventional administration schedule has already been demonstrated, there is no reported experience on the safety of these extracts with cluster schedules.We wanted to determine whether the use of a cluster schedule of a hypoallergenic allergen with a high concentration […]
Limonium tataricum (Lt) is a plant belonging to the family of Plumbaginaceae. The role of this family and in particular, that of dried flowers (but not of the pollen) in occupational allergy has already been described.We have observed a farmer with asthma occurring in the presence of fresh flowers. Standard methacoline test demonstrated that the […]
16 May 2014 / 23 May 2024 by almaware
Background: Asthma is a complex disease with numerous markers of severity/activity. Clinical assessment, functional parameters and inflammation biomarkers are the most used. A correlation between them is difficult, as each one evaluates a particular aspect of the disease. Objective and Methods: To explore the possible association between asthma control, pulmonary function and inflammation in patients […]
The assessment of the distribution of allergen skin test sensitizations is highly recommended for the optimal management of allergic respiratory conditions. We aimed at evaluating the distribution of allergen sensitizations in individuals with asthma and/or rhinitis in the Southern region of Italy, and at exploring whether changes in the frequency of allergen sensitizations occurred after […]
Background: To determine the effect of intranasal sodium hyaluronate on mucociliary clearance time following functional endoscopic sinus surgery in patients with nasal polyposis. Study Design: Randomized, controlled, blinded study. Methods: Thirty-six patients with grade II nasal polyposis undergoing functional endoscopic sinus surgery received intranasal sodium hyaluronate 9mg twice daily or saline for 30 days commencing […]
Background. Allergic rhinitis and asthma may be associated, bronchial hyperreactivity (BHR) is quite common in AR patients. It has been reported that allergen bronchial challenge induces nasal inflammation.Methacholine (MCH) is a stimulus able to elicit BHR.There is no study that investigated the effect ofMCH bronchial challenge on the nose.Objective. The aim of this study was […]
Background: The cross-reactive allergen responsible for the so called “mugwort-celeryspice-syndrome”, a pollen-food allergy that occurs in a minority of mugwort pollen-allergic patients, is still undefined.Objective: To identify the allergen responsible for the cross-reactivity between mugwort pollen and plant-derived foods. Methods: The serum from one index patient with both fennel and mugwort pollen allergy was used […]
Background. Specific immunotherapy (SIT) efficacy and safety by subcutaneous (SCIT) and sublingual (SLIT) route is supported by literature data. Pre-coseasonal treatment is currently the more accepted option for pollen immunotherapy in terms of costs and patient’s compliance. This retrospective study evaluated the patient’s preference concerning subcutaneous or sublingual route in pre-coseasonal treatment.Materials andmethods.We evaluated 145 […]