Original Article
16 May 2014 / 17 April 2024 by almaware
Background: To determine the effect of intranasal sodium hyaluronate on mucociliary clearance time following functional endoscopic sinus surgery in patients with nasal polyposis. Study Design: Randomized, controlled, blinded study. Methods: Thirty-six patients with grade II nasal polyposis undergoing functional endoscopic sinus surgery received intranasal sodium hyaluronate 9mg twice daily or saline for 30 days commencing […]
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Background. Allergic rhinitis and asthma may be associated, bronchial hyperreactivity (BHR) is quite common in AR patients. It has been reported that allergen bronchial challenge induces nasal inflammation.Methacholine (MCH) is a stimulus able to elicit BHR.There is no study that investigated the effect ofMCH bronchial challenge on the nose.Objective. The aim of this study was […]
Background: The cross-reactive allergen responsible for the so called “mugwort-celeryspice-syndrome”, a pollen-food allergy that occurs in a minority of mugwort pollen-allergic patients, is still undefined.Objective: To identify the allergen responsible for the cross-reactivity between mugwort pollen and plant-derived foods. Methods: The serum from one index patient with both fennel and mugwort pollen allergy was used […]
Background. Specific immunotherapy (SIT) efficacy and safety by subcutaneous (SCIT) and sublingual (SLIT) route is supported by literature data. Pre-coseasonal treatment is currently the more accepted option for pollen immunotherapy in terms of costs and patient’s compliance. This retrospective study evaluated the patient’s preference concerning subcutaneous or sublingual route in pre-coseasonal treatment.Materials andmethods.We evaluated 145 […]
In recent years there has been increasing prevalence of allergic diseases globally, especially in children.Many IgE-dependent allergic manifestations have been described in HIV-infected individuals. However, it seems to be controversial whether immunological changes, such as IgE elevation, results from the infection or is related to the presence of allergy in these subjects. The aim of […]
Background:The prevalence of IgE reactivity against genuine walnut and hazelnut allergens is poorly defined. Objective: The IgE response to walnut and hazelnut was investigated in Italian patients with primary allergy to these nuts. Methods: Sera from 36 patients allergic to hazelnut and/or walnut, not reactive to PR-10, profilin, and LTP, underwent immunoblot analysis with extracts […]
Background: Allergic rhinoconjunctivitis is a clinical condition that impairs quality of life.The use of traditional drugs in many cases is not enough to improve quality of life in these patients. Methods: In this pilot study we used the Sanispira Nasal filters in 15 patients (mean age 34,7 years) affected by allergic rhinoconjunctivitis for 18 days. […]
Background and Objective. Single SLIT studies with native allergen extracts support a dose-response effect for clinical and immunological outcomes. Conversely for carbamylated allergoids this dose-response effects is less evident, likely because the threshold for efficacy is more easily reached through the enhanced bioavailability of the extract consequent to the selective chemical modification. Thus this pilot […]
Background. Oral food challenge (OFC) is the gold standard for the diagnosis of food allergy (FA), but it is risky, expensive and time-consuming. Many studies aimed to avoid OFC by finding a cut off (CO) of skin prick test (SPT) to predict a positive outcome of OFC. Unfortunately the results of these studies are poorly […]
Limonium tataricum (Lt) is a plant belonging to the family of Plumbaginaceae. The role of this family and in particular, that of dried flowers (but not of the pollen) in occupational allergy has already been described.We have observed a farmer with asthma occurring in the presence of fresh flowers. Standard methacoline test demonstrated that the […]