Original Article
16 May 2014 / 17 April 2024 by almaware
Background. Allergic rhinitis and asthma may be associated, bronchial hyperreactivity (BHR) is quite common in AR patients. It has been reported that allergen bronchial challenge induces nasal inflammation.Methacholine (MCH) is a stimulus able to elicit BHR.There is no study that investigated the effect ofMCH bronchial challenge on the nose.Objective. The aim of this study was […]
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Background: The cross-reactive allergen responsible for the so called “mugwort-celeryspice-syndrome”, a pollen-food allergy that occurs in a minority of mugwort pollen-allergic patients, is still undefined.Objective: To identify the allergen responsible for the cross-reactivity between mugwort pollen and plant-derived foods. Methods: The serum from one index patient with both fennel and mugwort pollen allergy was used […]
Background. Specific immunotherapy (SIT) efficacy and safety by subcutaneous (SCIT) and sublingual (SLIT) route is supported by literature data. Pre-coseasonal treatment is currently the more accepted option for pollen immunotherapy in terms of costs and patient’s compliance. This retrospective study evaluated the patient’s preference concerning subcutaneous or sublingual route in pre-coseasonal treatment.Materials andmethods.We evaluated 145 […]
In recent years there has been increasing prevalence of allergic diseases globally, especially in children.Many IgE-dependent allergic manifestations have been described in HIV-infected individuals. However, it seems to be controversial whether immunological changes, such as IgE elevation, results from the infection or is related to the presence of allergy in these subjects. The aim of […]
Background:The prevalence of IgE reactivity against genuine walnut and hazelnut allergens is poorly defined. Objective: The IgE response to walnut and hazelnut was investigated in Italian patients with primary allergy to these nuts. Methods: Sera from 36 patients allergic to hazelnut and/or walnut, not reactive to PR-10, profilin, and LTP, underwent immunoblot analysis with extracts […]
15 May 2014 / 17 April 2024 by almaware
Background: Food is one of the leading causes of anaphylaxis. In the Netherlands, patients visit a general practitioner (GP) as often as an emergency department (ED) in case of an acute food allergic reaction. So far, the management of food allergic reactions by GPs has not been investigated. Therefore, we explored the management of acute […]
9 May 2014 / 17 April 2024 by almaware
Background. Specific subcutaneous immunotherapy (SCIT) is cost-effective; however its economical burden can lead to non-adherence. We aimed to identify the reported reasons, patient’s personal or socio-demographic characteristics and SCIT-related factors associated with non-adherence to SCIT. Methods. This is a cross-sectional, observational study held in a Portuguese University Hospital. All records from patients starting SCIT in […]
Oral food challenge (OFC) is still considered the gold standard for diagnosis of food allergy (FA). Skin prick test (SPT) and specific IgE (sIgE) tests are very useful but limited in their predictive accuracy. End point test (EPT) has been recently considered to determine the starting dose to induce oral desensitization. Allergometric tests combined may […]
Component resolved diagnosis (CRD) represents an innovative and revolutionary tool in allergy diagnosis. At the same time, some criticisms can be outlined. The present web survey aimed at investigating the role of CRD in daily clinical practice, according to a sample of Italian specialists who manage allergic patients. 127 physicians, mostly allergists, completed the questionnaire, […]
Usually, hyperresponsiveness to inhaled methacholine is considered closely associated with a diagnosis of bronchial asthma. Recently, it has been clearly pointed out that bronchial hyperreactivity (BHR) is not a constant feature of asthma and that this condition is not always related to airways inflammation.In the present study we evaluated 42 Patients (21 positive and 21 […]