Original Article
28 May 2014 / 17 April 2024 by almaware
Objective: We evaluated, by means of a multicentre, prospective observational trial, the severity in term of symptoms and symptomatic drugs use and the presence of asthma in subjects with tree or cypress or olive, or ragweed or parietaria allergy and we evaluated also the efficacy of a consecutive 2-year specific sublingual immunotherapy treatment. Patients and […]
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Background: Cross-reactions between venoms may be responsible for multiple diagnostic positivities in hymenoptera allergy. There is limited data on the cross-reactivity between Vespula spp and Vespa crabro, which is an important cause of severe reactions in some parts of Europe. We studied by CAP-inhibition assays and immunoblotting the cross-reactivity between the two venoms. Methods: Sera […]
Background: The micro-array techniques for the detection of specific IgE has improved the diagnostic procedures for allergic diseases. This method also allows to define sensitisation profiles from an epidemiological point of view.We studied the sensitisation pattern in a population of polysensitized patients with respiratory allergy, living in a restricted geographical area in the north-west Italy. […]
Guidelines recognize the importance of achieving and maintaining asthma control: the treatment strategies now available allow the control of the great majority of patients with asthma but despite many efforts only 5% of patients achieve guideline-defined asthma control. The GAPP (The Global Asthma Physician and Patient survey) is a global quantitative survey with the aim […]
Background: Sublingual immunotherapy (SLIT) with monomeric carbamylated allergoid proved to be well tolerated, safe and effective in patients with respiratory allergy. Standard administration regimens are expected to require a long time before clinical benefit can be appreciated. We investigated whether pre-seasonal and perennial regimens differently affect the clinical efficacy of grass pollen SLIT. Methods: Adult […]
Background: Primary apple allergy is frequent in Mediterranean countries where hypersensitivity to lipid transfer protein (LTP) is common. Due to its stability upon pepsin digestion, LTP may cause systemic allergic reactions. This study investigated the potential risk associated with an isolated intake of apple while fasting in LTP hypersensitive patients with clinical allergy to peach […]
Background: In birch pollen-allergic patients the occurrence of clinically relevant crossreactivity to plant-derived foods is clearly related with the level of birch-specific IgE. In profilin-hypersensitive patients this has not been investigated so far. Objective: To investigate whether the levels of profilin IgE are predictive of the development of food allergy in hypersensitive patients. Methods: IgE […]
Background: In multiple NSAID reactors, intolerance to weak COX-1 inhibitors may pose relevant therapeutic problems when painful, febrile or rheumatic disorders co-exist. Objective: To assess whether pre-medication with a second generation antihistamine is able to prevent urticaria induced by “alternative” NSAIDs. Methods: 87 with a history of urticaria following the administration of multiple, chemically unrelated […]
Background: The worldwide prevalence of allergic diseases such as rhinitis, asthma, and atopic dermatitis is continuously increasing, while other allergic disorders such as urticaria and angioedema are less investigated.We performed a population study evaluating the prevalence of any kind of allergic disorders. Methods: The entire population of 7,201 inhabitants of Cotignola (Ravenna, Italy) was surveyed […]
Childhood asthma presents with specific clinical and functional characteristics. The aim of our study was the description of a large cohort of asthmatic children. It was also to assess their outcome with maintenance therapy according to guidelines, and to analyze the relationship with baseline’s characteristics.We focused particularly on clinical and functional pediatric specificities. Methods: Prospective […]