Original Article
28 May 2014 / 17 April 2024 by almaware
The efficacy and safety of monomeric allergoid (Lofarma, Milan) have been demonstrated in adults but very few studies have examined it in children. This study therefore investigated the efficacy and safety of this sublingual immunotherapy (SLIT) at the dosage of 1000 AU five times a week without any up-dosing. Forty allergic children(17 M and 23 […]
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Background: There is some evidence suggesting that factors other than autoantibodies to FceRI or IgE and histamine released from mast cells may play a role in skin autoreactivity that characterizes many patients with chronic urticaria (CU) and, possibly, in the pathogenesis of this disease. Objective: The effect of antihistamine treatment on autologous plasma skin test (APST) […]
Introduction: High-resolution computed tomography (HRCT) is a widespread medical imaging method for the study of thoracic diseases. In asthma it is very useful particularly when it is difficult to achieve an effective control of disease, and in severe deterioration. Aim: It was intended to evaluate the imaging changes by HRCT in asthmatic patients and to […]
Purpose of the study: To detect the origin of ragweed pollen and to measure the impact of this pollen exposure on allergic patients, so their sensitivity can be noted (using specific IgE production: sIgEw1) in order to inform the population about an “allergy” against those ragweed pollen grains. Material and methods: To measure population exposure […]
Background: Kiwi allergy is frequent and can be the result of sensitization to a number of allergens showing different physicochemical characteristics. Component-resolved diagnosis of kiwi allergy is still unavailable in routine clinical practice. Objective: To investigate whether component resolved-diagnosis of kiwi allergy can be, at least in part, carried out by a proper combination of […]
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are a frequent cause of hypersensitivity reactions, therefore, in clinical practice, it’s important to find safe and effective substances. Objective: To evaluate the tolerability of etoricoxib and its subsequent actual use and safety at home. Methods: Etoricoxib tolerance was assessed by single-blindplacebo- controlled oral challenges and its subsequent use was […]
It has been demonstrated that Leukotriene modifiers reduce rhinitis symptoms, but montelukast preventive effect on inflammatory cells pattern in intranasal challenge studies has not been already assessed.This pilot study has been designed to explore the montelukast effects in preventing early/late inflammatory cells response to specific allergen challenge in persistent rhinitis. After a 4 week wash-out […]
Background: Sparse clinical observations suggest a possible association between food allergy to lipid transfer protein (LTP) and chronic urticaria (CU). Objective: To investigate the possible association between LTP hypersensitivity and CU. Methods: History of CU, and/or of NSAID hypersensitivity was prospectively assessed in 75 consecutive LTP-allergic subjects (M/F 27/48; age 33.6 years); those with positive […]
Background: food challenge is required to assess tolerance in cow milk (CM) allergy. A positive challenge contraindicates the reintroduction of CM. Specific oral tolerance induction (SOTI) is a promising treatment. Methods: all children admitted for a challenge were prospectively enrolled. To those tolerating between 2 and 150 ml a SOTI protocol was offered. Outcome, adverse […]
The definition of reference normal values for urinary LTE4 still represents an open question. Aim: to assess the influence of gender and age on urinary LTE4 levels in normal individuals. Methods: after their informed consent, urinary LTE4 was measured in 124 well matched, non smoker, non atopic subjects (mean age 49.5 y±20.1 sd; range 4-85 […]