Original Article
28 May 2014 / 17 April 2024 by almaware
Background: Sublingual immunotherapy (SLIT) with monomeric carbamylated allergoid proved to be well tolerated, safe and effective in patients with respiratory allergy. Standard administration regimens are expected to require a long time before clinical benefit can be appreciated. We investigated whether pre-seasonal and perennial regimens differently affect the clinical efficacy of grass pollen SLIT. Methods: Adult […]
Read more »
Background: Primary apple allergy is frequent in Mediterranean countries where hypersensitivity to lipid transfer protein (LTP) is common. Due to its stability upon pepsin digestion, LTP may cause systemic allergic reactions. This study investigated the potential risk associated with an isolated intake of apple while fasting in LTP hypersensitive patients with clinical allergy to peach […]
Background: In birch pollen-allergic patients the occurrence of clinically relevant crossreactivity to plant-derived foods is clearly related with the level of birch-specific IgE. In profilin-hypersensitive patients this has not been investigated so far. Objective: To investigate whether the levels of profilin IgE are predictive of the development of food allergy in hypersensitive patients. Methods: IgE […]
Background: In multiple NSAID reactors, intolerance to weak COX-1 inhibitors may pose relevant therapeutic problems when painful, febrile or rheumatic disorders co-exist. Objective: To assess whether pre-medication with a second generation antihistamine is able to prevent urticaria induced by “alternative” NSAIDs. Methods: 87 with a history of urticaria following the administration of multiple, chemically unrelated […]
Background: The worldwide prevalence of allergic diseases such as rhinitis, asthma, and atopic dermatitis is continuously increasing, while other allergic disorders such as urticaria and angioedema are less investigated.We performed a population study evaluating the prevalence of any kind of allergic disorders. Methods: The entire population of 7,201 inhabitants of Cotignola (Ravenna, Italy) was surveyed […]
Childhood asthma presents with specific clinical and functional characteristics. The aim of our study was the description of a large cohort of asthmatic children. It was also to assess their outcome with maintenance therapy according to guidelines, and to analyze the relationship with baseline’s characteristics.We focused particularly on clinical and functional pediatric specificities. Methods: Prospective […]
Background: Inhaled combined therapy improves the pulmonary function in asthmatic patients. The effect on the airway hyperresponsiveness (AHR) and the efficacy of different pharmacological schedules is not well clarified on adolescent asthmatics. Objective: Evaluate the responses to different combined inhaled therapies in adolescent asthmatics and study its impact on exercise induced AHR. Methods: Basal lung […]
Background: Lipid transfer proteins (LTP) are pan-allergens in plant derived foods that have been also detected in several pollens. The observed cross-reactivity between pollen and plant-food LTPs has led to hypothesize that primary sensitisation to this allergen may occur through the airways. Objective: The present study looked at the prevalence of hypersensitivity to different LTP-containing […]
Background: specific oral tolerance induction (SOTI) is a promising approach in the treatment of severe food allergies. Different protocols have demonstrated its efficacy. Nevertheless, SOTI is still considered an experimental method and should be limited to highly controlled settings. Aims: to define the incidence and severity of adverse reactions, possible risk factors, and the safety […]
Purpose of the study: To detect the origin of ragweed pollen and to measure the impact of this pollen exposure on allergic patients, so their sensitivity can be noted (using specific IgE production: sIgEw1) in order to inform the population about an “allergy” against those ragweed pollen grains. Material and methods: To measure population exposure […]