Original Article
29 May 2014 / 17 April 2024 by almaware
Prevention of anaphylaxis depends on optimal management of patient-related risk factors, an educational programme to teach how to avoid confirmed relevant allergens. We observed in our routine practice several patients who underwent allergological evaluation months or years after the occurrence of anaphylactic reaction or a relapse. The main issues of this proposal are to identify […]
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Adrenaline (epinephrine) is the first line drug to be given in anaphylaxis and can save patients’ lives. Conversely, incorrect administration of adrenaline in anaphylaxis has caused patients serious harm, including death. We compared the survey results of doctors’ knowledge of adrenaline administration in adults of two District General Hospitals Trusts in England and found, that […]
Objective: A double-blind, placebo-controlled study was performed with 37 patients to assess the efficacy as well as the safety of short-term pre-seasonal subcutaneous immunotherapy (SCIT) with a six-grass pollen allergoid for one year. Results: After one pre-seasonal treatment cycle there are significant differences between the groups in favour of active treatment. On a “1 – […]
Background: Most clinical trials investigating preventive and disease-modifying effects of SCIT were performed in children for only a few allergen products. In this study we observed adult patients 3 years after the completion of treatment with a high-dose hypoallergenic 6-grass pollen preparation.Methods: A double-blind, placebo-controlled (DBPC) trial had proven efficacy and safety of a high-dose […]
Background: Previous surveys performed in this area showed that the age at onset of ragweed allergy in monosensitized subjects is about 35. Objective: To detect whether a reduction in the mean age of ragweed sensitization in the area of Milan has taken place after the last survey. Methods: All patients developing clinical ragweed pollen allergy […]
Background. Aspirin hypersensitivity may represent a major problem in patients with ischemic coronary disease who need a stenting procedure. In those patients, clinically unsettled, reasonably quick desensitisation procedures are needed. In our study we attempted to select the most suitable procedure on the basis of characteristics and severity of ASA hypersensitivity. MethodsThirty patients with a […]
Background: Molecular allergens enable the definition of sensitization profiles in allergic patients. Aim: to validate the most helpful allergens for the diagnosis of latex allergy in different clinical situations.Methods: 130 patients suspected to be allergic to latex with positive IgE against natural rubber latex (NRL) have been studied: 97 were confirmed as latex allergic (among […]
Introduction.T cell receptor excision circles (TREC) on CD31+T cells are related to recent thymic emigrant cells (RTEs). The involvement of the functional thymic tissue occurs early in the IgE-mediated allergic reaction, and in response to specific immunotherapy (SIT). Aim. Evaluation of specific immunotherapy effects on TREC number in peripheral T cells in patients allergic to […]
Eotaxin is a potent agonist for CC chemokine receptor 3 that can attract eosinophils at sites of inflammation. Given the potential role of eosinophils in chronic spontaneous urticaria (CU), we measured serum eotaxin levels together with C-reactive protein in 100 CU patients who were characterized according to autologous serum skin test (ASST) and disease severity. […]
Background: Most Health Care Systems consider Continuing Medical Education a potential tool to improve quality of care and reduce disease management costs. Its efficacy in general practitioners needs to be further explored. Objective: This study assesses the effectiveness of a one-year continuing medical education/ continuing professional development course for general practitioners, regarding the improvement in […]