Original Article
29 May 2014 / 17 April 2024 by almaware
Background: Extra-European immigrants are increasingly seen in allergy clinics. In view of their different genetic background they represent an opportunity to investigate the dynamics of sensitization to airborne allergens. Objective: We investigated the pattern of airborne sensitization among allergic extra-European immigrants living in two areas of northern Italy.Methods: Extra-European immigrants living in Milan and Verona […]
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Metamizol is a pyrazolone-derivative nonsteroidal anti-inflammatory drug that is commonly associated with hypersensitivity reactions. Some of these reactions are IgEmediated and potentially severe, which limits the diagnosis based on oral drug challenge. We describe 6 selective metamizol hypersensitivity cases, regarding clinical evaluation and diagnosis management, with focus on the usefulness of skin tests and the […]
Prevention of anaphylaxis depends on optimal management of patient-related risk factors, an educational programme to teach how to avoid confirmed relevant allergens. We observed in our routine practice several patients who underwent allergological evaluation months or years after the occurrence of anaphylactic reaction or a relapse. The main issues of this proposal are to identify […]
Adrenaline (epinephrine) is the first line drug to be given in anaphylaxis and can save patients’ lives. Conversely, incorrect administration of adrenaline in anaphylaxis has caused patients serious harm, including death. We compared the survey results of doctors’ knowledge of adrenaline administration in adults of two District General Hospitals Trusts in England and found, that […]
Objective: A double-blind, placebo-controlled study was performed with 37 patients to assess the efficacy as well as the safety of short-term pre-seasonal subcutaneous immunotherapy (SCIT) with a six-grass pollen allergoid for one year. Results: After one pre-seasonal treatment cycle there are significant differences between the groups in favour of active treatment. On a “1 – […]
Background: Most clinical trials investigating preventive and disease-modifying effects of SCIT were performed in children for only a few allergen products. In this study we observed adult patients 3 years after the completion of treatment with a high-dose hypoallergenic 6-grass pollen preparation.Methods: A double-blind, placebo-controlled (DBPC) trial had proven efficacy and safety of a high-dose […]
Background: Previous surveys performed in this area showed that the age at onset of ragweed allergy in monosensitized subjects is about 35. Objective: To detect whether a reduction in the mean age of ragweed sensitization in the area of Milan has taken place after the last survey. Methods: All patients developing clinical ragweed pollen allergy […]
Background. Aspirin hypersensitivity may represent a major problem in patients with ischemic coronary disease who need a stenting procedure. In those patients, clinically unsettled, reasonably quick desensitisation procedures are needed. In our study we attempted to select the most suitable procedure on the basis of characteristics and severity of ASA hypersensitivity. MethodsThirty patients with a […]
Some of the most recent advances in the diagnosis and treatment of childhood asthma and allergies are here reviewed. New perspectives have been opened by in vitro diagnostic tests for allergies based on a molecular approach and novel approaches to in vivo tests (SPT or FEno). A better characterization of the patients is opening new […]
Background: Oilseed rape and maize crops represent a large part of agriculture fields in European countries. Objective: To establish the actual prevalence of sensitization to oilseed rape and maize pollen, and to determine if this is correlated to the amount of exposure as well as to the patient’s history of atopy or asymptomatic atopy. Methods: […]