Original Article
29 May 2014 / 17 April 2024 by almaware
Background: Previous surveys performed in this area showed that the age at onset of ragweed allergy in monosensitized subjects is about 35. Objective: To detect whether a reduction in the mean age of ragweed sensitization in the area of Milan has taken place after the last survey. Methods: All patients developing clinical ragweed pollen allergy […]
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Background. Aspirin hypersensitivity may represent a major problem in patients with ischemic coronary disease who need a stenting procedure. In those patients, clinically unsettled, reasonably quick desensitisation procedures are needed. In our study we attempted to select the most suitable procedure on the basis of characteristics and severity of ASA hypersensitivity. MethodsThirty patients with a […]
Background: Molecular allergens enable the definition of sensitization profiles in allergic patients. Aim: to validate the most helpful allergens for the diagnosis of latex allergy in different clinical situations.Methods: 130 patients suspected to be allergic to latex with positive IgE against natural rubber latex (NRL) have been studied: 97 were confirmed as latex allergic (among […]
Introduction.T cell receptor excision circles (TREC) on CD31+T cells are related to recent thymic emigrant cells (RTEs). The involvement of the functional thymic tissue occurs early in the IgE-mediated allergic reaction, and in response to specific immunotherapy (SIT). Aim. Evaluation of specific immunotherapy effects on TREC number in peripheral T cells in patients allergic to […]
Background: Extra-European immigrants are increasingly seen in allergy clinics. In view of their different genetic background they represent an opportunity to investigate the dynamics of sensitization to airborne allergens. Objective: We investigated the pattern of airborne sensitization among allergic extra-European immigrants living in two areas of northern Italy.Methods: Extra-European immigrants living in Milan and Verona […]
Metamizol is a pyrazolone-derivative nonsteroidal anti-inflammatory drug that is commonly associated with hypersensitivity reactions. Some of these reactions are IgEmediated and potentially severe, which limits the diagnosis based on oral drug challenge. We describe 6 selective metamizol hypersensitivity cases, regarding clinical evaluation and diagnosis management, with focus on the usefulness of skin tests and the […]
Prevention of anaphylaxis depends on optimal management of patient-related risk factors, an educational programme to teach how to avoid confirmed relevant allergens. We observed in our routine practice several patients who underwent allergological evaluation months or years after the occurrence of anaphylactic reaction or a relapse. The main issues of this proposal are to identify […]
Eotaxin is a potent agonist for CC chemokine receptor 3 that can attract eosinophils at sites of inflammation. Given the potential role of eosinophils in chronic spontaneous urticaria (CU), we measured serum eotaxin levels together with C-reactive protein in 100 CU patients who were characterized according to autologous serum skin test (ASST) and disease severity. […]
Background: Most Health Care Systems consider Continuing Medical Education a potential tool to improve quality of care and reduce disease management costs. Its efficacy in general practitioners needs to be further explored. Objective: This study assesses the effectiveness of a one-year continuing medical education/ continuing professional development course for general practitioners, regarding the improvement in […]
Background: Until now no data on allergic sensitization to rodents allergens in Western Europe and Italy are available. The aim of this report was to investigate clinical significance and characteristics of IgE-mediated sensitization to mouse/rat (M/Rt) allergens in atopic subjects not occupationally exposed to these animals and living in urban area of Naples. Methods: In […]