Original Article
10 November 2014 / 17 April 2024 by almaware
Chronic urticaria (CU) is one of the most puzzling clinical entities confronted by the medical profession. It is a common motive for consultation, and in a sizable proportion of patients no identifiable cause is evident. Since there are relatively few publications regarding CU in developing countries, we performed a prospective 3-year study on the demographic […]
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Forecasting symptoms of pollen-related allergic rhinoconjunctivitis at the level of individual patients would be useful to improve disease control and plan pharmacological intervention. Information Technology nowadays facilitates a more efficient and easier monitoring of patients with chronic diseases. We aimed this study at testing the efficiency of a model to short-term forecast symptoms of pollen-AR […]
10 September 2014 / 23 May 2024 by almaware
Little is known about the prevalence and clinical relevance of sensitization to shrimp allergens other than tropomyosin. Objective. We detected the prevalence of arginine kinase and sarcoplasmic calcium binding protein sensitization, and identified a high molecular weight allergen that is frequently recognized by Italian shrimp-allergic patients. Methods.Sera from 40 shrimp-allergic patients underwent the detection of […]
9 September 2014 / 23 May 2024 by almaware
Rhinitis comprises several diseases with varying causes and different clinical manifestations and pathological features, but treated as a single clinical disorder. As heterogeneous disease, proper differential diagnosis is useful to delineate appropriate therapeutic intervention. Comparative proteomic investigation was aimed to provide information for specific differentially expressed proteins in rhino pathologic state, that could be used […]
16 July 2014 / 17 April 2024 by almaware
Background and Aim. This questionnaire-based study evaluated the overall level of knowledge about allergen-specific immunotherapy (SIT) among chest physicians, who are frequently involved in the management of respiratory allergies. This represents an interesting aspect, because chest physicians intercept many of the patients with allergic rhinitis w/wo asthma, in which SIT could be potentially indicated. Methods. […]
Background. Tetranychus urticae is a phytophagus mite found in the leaves of numerous plants. High sensitization rates have been demonstrated, however, provocation tests have only been performed in an occupational setting. Objective. To assess accuracy of skin prick tests and clinical relevance of T. urticae sensitization by means of conjunctival provocation tests (CPT) in a […]
Background. Lipid transfer protein (LTP) is a widely cross-reacting allergen in plant foods.Objective. To assess whether IgE to vegetable foods show predictable trends in LTP allergic patients. Methods. Clinical allergy to plant foods other than peach was sought in 15 consecutive peach-allergic adults monosensitized to LTP. IgE specific for peach, apple, hazelnut, walnut, peanut, lentil, […]
29 May 2014 / 17 April 2024 by almaware
Background: Molecular allergens enable the definition of sensitization profiles in allergic patients. Aim: to validate the most helpful allergens for the diagnosis of latex allergy in different clinical situations.Methods: 130 patients suspected to be allergic to latex with positive IgE against natural rubber latex (NRL) have been studied: 97 were confirmed as latex allergic (among […]
Introduction.T cell receptor excision circles (TREC) on CD31+T cells are related to recent thymic emigrant cells (RTEs). The involvement of the functional thymic tissue occurs early in the IgE-mediated allergic reaction, and in response to specific immunotherapy (SIT). Aim. Evaluation of specific immunotherapy effects on TREC number in peripheral T cells in patients allergic to […]
Background: Extra-European immigrants are increasingly seen in allergy clinics. In view of their different genetic background they represent an opportunity to investigate the dynamics of sensitization to airborne allergens. Objective: We investigated the pattern of airborne sensitization among allergic extra-European immigrants living in two areas of northern Italy.Methods: Extra-European immigrants living in Milan and Verona […]