Original Article
16 July 2014 / 17 April 2024 by almaware
Background and Aim. This questionnaire-based study evaluated the overall level of knowledge about allergen-specific immunotherapy (SIT) among chest physicians, who are frequently involved in the management of respiratory allergies. This represents an interesting aspect, because chest physicians intercept many of the patients with allergic rhinitis w/wo asthma, in which SIT could be potentially indicated. Methods. […]
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Background. Tetranychus urticae is a phytophagus mite found in the leaves of numerous plants. High sensitization rates have been demonstrated, however, provocation tests have only been performed in an occupational setting. Objective. To assess accuracy of skin prick tests and clinical relevance of T. urticae sensitization by means of conjunctival provocation tests (CPT) in a […]
Background. Lipid transfer protein (LTP) is a widely cross-reacting allergen in plant foods.Objective. To assess whether IgE to vegetable foods show predictable trends in LTP allergic patients. Methods. Clinical allergy to plant foods other than peach was sought in 15 consecutive peach-allergic adults monosensitized to LTP. IgE specific for peach, apple, hazelnut, walnut, peanut, lentil, […]
29 May 2014 / 17 April 2024 by almaware
Background: Molecular allergens enable the definition of sensitization profiles in allergic patients. Aim: to validate the most helpful allergens for the diagnosis of latex allergy in different clinical situations.Methods: 130 patients suspected to be allergic to latex with positive IgE against natural rubber latex (NRL) have been studied: 97 were confirmed as latex allergic (among […]
Introduction.T cell receptor excision circles (TREC) on CD31+T cells are related to recent thymic emigrant cells (RTEs). The involvement of the functional thymic tissue occurs early in the IgE-mediated allergic reaction, and in response to specific immunotherapy (SIT). Aim. Evaluation of specific immunotherapy effects on TREC number in peripheral T cells in patients allergic to […]
Background: Extra-European immigrants are increasingly seen in allergy clinics. In view of their different genetic background they represent an opportunity to investigate the dynamics of sensitization to airborne allergens. Objective: We investigated the pattern of airborne sensitization among allergic extra-European immigrants living in two areas of northern Italy.Methods: Extra-European immigrants living in Milan and Verona […]
Metamizol is a pyrazolone-derivative nonsteroidal anti-inflammatory drug that is commonly associated with hypersensitivity reactions. Some of these reactions are IgEmediated and potentially severe, which limits the diagnosis based on oral drug challenge. We describe 6 selective metamizol hypersensitivity cases, regarding clinical evaluation and diagnosis management, with focus on the usefulness of skin tests and the […]
Prevention of anaphylaxis depends on optimal management of patient-related risk factors, an educational programme to teach how to avoid confirmed relevant allergens. We observed in our routine practice several patients who underwent allergological evaluation months or years after the occurrence of anaphylactic reaction or a relapse. The main issues of this proposal are to identify […]
Adrenaline (epinephrine) is the first line drug to be given in anaphylaxis and can save patients’ lives. Conversely, incorrect administration of adrenaline in anaphylaxis has caused patients serious harm, including death. We compared the survey results of doctors’ knowledge of adrenaline administration in adults of two District General Hospitals Trusts in England and found, that […]
Objective: A double-blind, placebo-controlled study was performed with 37 patients to assess the efficacy as well as the safety of short-term pre-seasonal subcutaneous immunotherapy (SCIT) with a six-grass pollen allergoid for one year. Results: After one pre-seasonal treatment cycle there are significant differences between the groups in favour of active treatment. On a “1 – […]