Original Article
9 September 2014 / 23 May 2024 by almaware
Rhinitis comprises several diseases with varying causes and different clinical manifestations and pathological features, but treated as a single clinical disorder. As heterogeneous disease, proper differential diagnosis is useful to delineate appropriate therapeutic intervention. Comparative proteomic investigation was aimed to provide information for specific differentially expressed proteins in rhino pathologic state, that could be used […]
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16 July 2014 / 17 April 2024 by almaware
Background and Aim. This questionnaire-based study evaluated the overall level of knowledge about allergen-specific immunotherapy (SIT) among chest physicians, who are frequently involved in the management of respiratory allergies. This represents an interesting aspect, because chest physicians intercept many of the patients with allergic rhinitis w/wo asthma, in which SIT could be potentially indicated. Methods. […]
Background. Tetranychus urticae is a phytophagus mite found in the leaves of numerous plants. High sensitization rates have been demonstrated, however, provocation tests have only been performed in an occupational setting. Objective. To assess accuracy of skin prick tests and clinical relevance of T. urticae sensitization by means of conjunctival provocation tests (CPT) in a […]
Background. Lipid transfer protein (LTP) is a widely cross-reacting allergen in plant foods.Objective. To assess whether IgE to vegetable foods show predictable trends in LTP allergic patients. Methods. Clinical allergy to plant foods other than peach was sought in 15 consecutive peach-allergic adults monosensitized to LTP. IgE specific for peach, apple, hazelnut, walnut, peanut, lentil, […]
29 May 2014 / 17 April 2024 by almaware
Prevention of anaphylaxis depends on optimal management of patient-related risk factors, an educational programme to teach how to avoid confirmed relevant allergens. We observed in our routine practice several patients who underwent allergological evaluation months or years after the occurrence of anaphylactic reaction or a relapse. The main issues of this proposal are to identify […]
Adrenaline (epinephrine) is the first line drug to be given in anaphylaxis and can save patients’ lives. Conversely, incorrect administration of adrenaline in anaphylaxis has caused patients serious harm, including death. We compared the survey results of doctors’ knowledge of adrenaline administration in adults of two District General Hospitals Trusts in England and found, that […]
Objective: A double-blind, placebo-controlled study was performed with 37 patients to assess the efficacy as well as the safety of short-term pre-seasonal subcutaneous immunotherapy (SCIT) with a six-grass pollen allergoid for one year. Results: After one pre-seasonal treatment cycle there are significant differences between the groups in favour of active treatment. On a “1 – […]
Background: Most clinical trials investigating preventive and disease-modifying effects of SCIT were performed in children for only a few allergen products. In this study we observed adult patients 3 years after the completion of treatment with a high-dose hypoallergenic 6-grass pollen preparation.Methods: A double-blind, placebo-controlled (DBPC) trial had proven efficacy and safety of a high-dose […]
Background: Previous surveys performed in this area showed that the age at onset of ragweed allergy in monosensitized subjects is about 35. Objective: To detect whether a reduction in the mean age of ragweed sensitization in the area of Milan has taken place after the last survey. Methods: All patients developing clinical ragweed pollen allergy […]
Background. Aspirin hypersensitivity may represent a major problem in patients with ischemic coronary disease who need a stenting procedure. In those patients, clinically unsettled, reasonably quick desensitisation procedures are needed. In our study we attempted to select the most suitable procedure on the basis of characteristics and severity of ASA hypersensitivity. MethodsThirty patients with a […]