Original Article
16 May 2014 / 17 April 2024 by almaware
Background and Objective. Single SLIT studies with native allergen extracts support a dose-response effect for clinical and immunological outcomes. Conversely for carbamylated allergoids this dose-response effects is less evident, likely because the threshold for efficacy is more easily reached through the enhanced bioavailability of the extract consequent to the selective chemical modification. Thus this pilot […]
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Review
Allergen-specific Immunotherapy (AIT) is a well-documented etiological therapy for IgE-mediated rhinitis and asthma and it is the only treatment strategy able to alter the natural history of the diseases. This review aims at focusing some real-life aspects of AIT. In spite of the high level of evidence for efficacy and safety reached by AIT and […]
Case Report
Multiple sclerosis is a disease with a potentially severe prognosis and epidemiologically increasing. Interferon beta 1a is a very useful maintenance therapy widely used by neurologists. In the literature, there are several case reports of hypersensitivity reactions. In this case report we describe an anaphylactic IgE mediated reaction to interferon beta 1a. We also describe, […]
We present a case of acute generalized exanthematous pustolosis (AGEP) induced by amoxicillin-clavulanate. Clinical diagnosis was confirmed by symptoms presentation and histological features (Euroscar score point compatible with definite diagnosis).Patch testing performer six months later confirmed sensitization to the culprit drug and showed positivity also to other beta-lactam antibiotics (penicillin G and cephalexin). We believe […]
Human recombinant erythropoietins (EPO) and darbepoetins are widely used for anemias associated with chronic kidney disease. Allergic reactions to erythropoetins and darbepoetins have only occasionally been reported. These skin reactions include pruritus, wheals at the injection site, orofacial anaphylaxis and anjioedema. In this article, we report an 11 year-old female who experienced generalized erithematous skin […]
Background: Allergic rhinoconjunctivitis is a clinical condition that impairs quality of life.The use of traditional drugs in many cases is not enough to improve quality of life in these patients. Methods: In this pilot study we used the Sanispira Nasal filters in 15 patients (mean age 34,7 years) affected by allergic rhinoconjunctivitis for 18 days. […]
Background:The prevalence of IgE reactivity against genuine walnut and hazelnut allergens is poorly defined. Objective: The IgE response to walnut and hazelnut was investigated in Italian patients with primary allergy to these nuts. Methods: Sera from 36 patients allergic to hazelnut and/or walnut, not reactive to PR-10, profilin, and LTP, underwent immunoblot analysis with extracts […]
In recent years there has been increasing prevalence of allergic diseases globally, especially in children.Many IgE-dependent allergic manifestations have been described in HIV-infected individuals. However, it seems to be controversial whether immunological changes, such as IgE elevation, results from the infection or is related to the presence of allergy in these subjects. The aim of […]
Letter to the Editor
16 May 2014 / 23 May 2024 by almaware
This study reports a case of anaphylaxis to a home-madewine and tolerance to other wines.