Review
28 May 2014 / 17 April 2024 by almaware
Mite allergens from the Pyroglyphidae family are the most frequent and potent sources of perennial asthma and rhinitis. Since 1988 molecular knowledge has considerably increased and structures and functions have been determined for most of them. Of the 22 denominated allergens, Der p 1 and Der p 2 are major allergens recognized by more than […]
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Preschool children frequently suffer from acute respiratory tract infections (ARTI). Immunostimulants (ISs) are often administered to reduce their impact. This study aimed to establish the efficacy of ISs in the prevention of pediatric ARTI through the analysis of systematic reviews (SRs). We explored Medline database in October 2010 limiting our search to SRs, that included […]
Although asthma has always been considered as a disease of the early years, its presence is found both in old and young people. Asthma is often underestimated in the elderly because it can be confused with other diseases such as heart failure and, frequently, with COPD. In most cases asthmatic patients develop their disease before […]
25 May 2014 / 17 April 2024 by almaware
Rare allergens in indoor environment are insufficiently recognized. The sources are diverse: they include animal, namely acaride, insect and mammalian allergens or vegetable allergens. The prevalence of sensitization to rare allergens depends on geographical and climatological characteristics, on people’s habits and overall on dwelling specificities. Sensitizations to new rare allergens should be confirmed by documented […]
20 May 2014 / 17 April 2024 by almaware
Urticaria is a rash, that typically involves skin and mucosa, and is characterized by lesions known as hives or wheals. In some cases there is an involvement of deep dermis and subcutaneous tissue that causes a skin/mucosa manifestation called angioedema.Urticaria and angioedema are very often associated: urticaria-angioedema syndrome.The acute episodic form is the most prevalent […]
Wheat grain is a major staple of our diet. However, proteins derived from wheat grain have been implicated in both respiratory and food allergies, as well as in contact hypersensitivity. Numerous wheat allergens are present in the different fractions of wheat grain: a-amylase/trypsin inhibitor and lipid transfer protein are found in the water/salt soluble fraction, […]
Lactose malabsorption is a very common condition characterized by intestinal lactase deficiency. Primary lactose malabsorption is an inherited deficit present in the majority of the world’s population, while secondary hypolactasia can be the consequence of an intestinal disease. The presence of malabsorbed lactose in the colonic lumen may cause gastrointestinal symptoms. This condition is known […]
Oral food challenges are indicated for the diagnosis of food allergy and the doubleblind, placebo-controlled oral food challenge is considered the gold standard diagnostic method in children with suspected food allergy. This practice parameter for oral food challenges in children was prepared by a workgroup at the request of the French Society for Allergology and […]
16 May 2014 / 17 April 2024 by almaware
House dust mites (HDM) are one of the most important sources of indoor allergens worldwide.Exposure to high environmental levels of dust mite allergen is associated with an increased risk of sensitization, asthma and deterioration of lung function. On the basis of these data, it would be logical to assume that asthmatic patients with mite allergy […]
Allergen-specific Immunotherapy (AIT) is a well-documented etiological therapy for IgE-mediated rhinitis and asthma and it is the only treatment strategy able to alter the natural history of the diseases. This review aims at focusing some real-life aspects of AIT. In spite of the high level of evidence for efficacy and safety reached by AIT and […]