Original Article
9 September 2021 / 23 May 2024 by almaware
Background and objective. Although the administration of single-allergen extractsis recommended, there are polysensitized patients who require a different strategy. This study evaluates the effectiveness of an extract containing a mixture of house dust mites (HDM) and mold allergens in polysensitized patients withasthma and/or rhinitis. Methods. Using validated questionnaires, we assessed asthma and rhinitis control and quality […]
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9 September 2021 / 17 April 2024 by almaware
Cypress pollen allergy was virtually absent in Lombardy about 30 years ago. A 15-year clinical survey on cypress pollen sensitization and allergy in the area north of Milan reveals that both cypress pollen sensitization and allergy increased steadily from 2003 to 2017 along with the prevalence of clinical allergy over sensitization. The pollen concentration data, […]
Objective. The Test for Respiratory and Asthma Control in Kids (TRACK) is a tool to assess asthma control in preschool children. This study aims to validate the Portuguese from Portugal version of the TRACK questionnaire. Methods. A prospective cohort study was carried out to assess their psychometric characteristics. Caregivers of 141 children under age 5 with asthma symptoms […]
24 June 2021 / 17 April 2024 by almaware
Background. Different clinical pictures are related to corticosteroids (CS) non immediate hypersensitivity and the frequency of these reactions can be underestimated. The classification of CS in 3 groups and the identification of two patient’s profiles has been proposed by Baeck to help clinicians in the management of these cases. Methods. Data of 14 patients with […]
24 June 2021 / 23 May 2024 by almaware
Introduction. Most patients with primary and secondary immunodeficiencies need regular Intravenous Immunoglobulin (IVIG) or Subcutaneous Immunoglobulin (SCIG) treatment. This study aimed to evaluate the serum IgG trough levels, frequency of mild and severe infections, frequency and duration of hospitalization, duration of absence of school, and quality of life in patients switching their IVIG therapy to SCIG […]
Background. Climate conditions in the northwest of Spain are from the rest of the country, and the pollen sensitisation rates and allergens involved are different. The present study aimed to investigate the sensitisation profile of patients with grass pollen allergy and the interference of other sensitisations in respiratory symptoms. Methods. A total of 959 Spanish patients with seasonal […]
21 June 2021 / 17 April 2024 by almaware
The potential of IgG antibodies as allergy regulators has been discussed for decades and was brought to light that anti-allergen IgG is related to allergy inhibition in children during the first years of life and that IgG repertoire can differ between atopic and non-atopic individuals. Here, we aimed to evaluate in vitro the differential effects […]
The clinical usefulness of two commercial peach extracts for SPT (by Lofarma SpA and ALK-Abellò, respectively) was compared in a multicenter study carried out in Italy. Peach allergic patients were tested with the two extracts in parallel and underwent the detection of IgE specific for all three peach allergens currently available (Pru p 1, Pru […]
23 April 2021 / 17 April 2024 by almaware
Background. The Italian Registry on Severe Asthma (IRSA) is the most recent and largest registry in Italy. Objective. To improve the knowledge on the clinical and biological features of severe asthma (SA), and to monitor its treatments. Methods. To analyze clinical, functional, inflammatory, and treatment characteristics of severe asthmatics from the IRSA registry. Results. 851 […]
23 April 2021 / 23 May 2024 by almaware
Objective. CD4+T cell subtypes are the central orchestrators of airway inflammation in bronchialasthma (BA); however, the mechanisms that regulate their accumulation in asthmatic airways are still a challenging subject. In addition, neutrophils play a significant role in the development of airway remodeling and their presence may influence clinical presentation of BA being linked to the development […]