Original Article
28 May 2014 / 17 April 2024 by almaware
Background: Studies suggest a link between vitamin D deficiency and development of asthma and allergic diseases. Aim: To determine a) the association between vitamin D and asthma among children , b) difference in level of vitamin D in asthmatic children and control, and c) effect of vitamin D on atopy markers. Setting: Case-control study done, […]
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Background: Olive pollen sensitization is surprisingly frequent in Milan, an area that is virtually both olive- and ash-free.Objective:To establish the prevalence of olive pollen sensitization north of Milan, and to investigate the allergens involved.Methods: 300 pollenallergic patients living in this area were randomly selected. Based on SPT-results, olive pollen reactors were classified as multi-sensitized, oligo-sensitized, […]
Review
Recent observations suggest that pollen do not only interacts with the human immune system to elicit an allergic response in susceptible individuals. It would have a much broader impact on human health. This applies more especially, yet not exclusively, to three groups of diseases: non-allergic respiratory conditions, cardio- and cerebrovascular accidents, and psychiatric disorders including […]
Editorial
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Case Report
Food protein induced enterocolitis syndrome (FPIES) is a food-related non-IgE-mediated gastrointestinal hypersensitivity disorder. Atypical FPIES is characterized by the presence of specific IgE for the causative food. The guidelines suggested for diagnostic Oral Food Challenge in pediatric patients affected by suspected FPIES are different from the ones for children with IgE-mediated food allergy. We describe […]
Letter to the Editor
A 3-year prospective post marketing survey on the safety of the recently developed ultrashort pre-seasonal subcutaneous immunotherapy (uSCIT-MPL4) with pollen allergoids adjuvanted with monophosphoryl lipid A was performed. A total of 510 patients received uSCIT-MPL4, 61% for grass, 35.7% for birch, 13.2% for parietaria and 3% for other pollens (ragweed, mugwort, and olive). A total […]
Background: The allergenic profile of patients hypersensitive to pollen pan-allergens, profilin and polcalcin, has received little attention so far. Objective: To detect whether hypersensitivity to profilin and polcalcin follows sensitization to specific allergen sources or represents a primary phenomenon, and to examine the sensitization profiles of patients hypersensitive to pollen pan-allergens. Methods: IgE reactivity to […]
Objective: Omalizumab (OM), an innovative biological treatment for difficult asthma with perennial sensitisations, is an humanized monoclonal anti-IgE antibody that binds free circulating IgE; inhibits mast cell and basophil activation by combining free IgE, leads to IgE receptor down-regulation, thus blocking the inflammatory cascade. AIM of the study was to assess real-world cost-utility of add-on […]
Pollen allergens of the Poaceae family comprise one of the main causes of pollinosis worldwide. Although most of cereals are included in this family, certain pollination characteristics and aerobiological features differentiate them from common wild grass pollen. Cereal pollen grains cannot be easily characterised as potential sources of aeroallergens, because of their pollination mode (most […]
Commemoration