Original Article
9 May 2014 / 17 April 2024 by almaware
Usually, hyperresponsiveness to inhaled methacholine is considered closely associated with a diagnosis of bronchial asthma. Recently, it has been clearly pointed out that bronchial hyperreactivity (BHR) is not a constant feature of asthma and that this condition is not always related to airways inflammation.In the present study we evaluated 42 Patients (21 positive and 21 […]
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Component resolved diagnosis (CRD) represents an innovative and revolutionary tool in allergy diagnosis. At the same time, some criticisms can be outlined. The present web survey aimed at investigating the role of CRD in daily clinical practice, according to a sample of Italian specialists who manage allergic patients. 127 physicians, mostly allergists, completed the questionnaire, […]
Oral food challenge (OFC) is still considered the gold standard for diagnosis of food allergy (FA). Skin prick test (SPT) and specific IgE (sIgE) tests are very useful but limited in their predictive accuracy. End point test (EPT) has been recently considered to determine the starting dose to induce oral desensitization. Allergometric tests combined may […]
Case Report
We report the case of a 73 year old man on chronic aspirin therapy who went in anaphylactic shock during his daily farm chores following a meal rich in wheat products. The serum specific IgE assay (ImmunoCAP) showed strong positive specific IgE responses to ù-5 gliadin. A two-year period avoiding wheat meals 3 hours prior […]
Background. Specific subcutaneous immunotherapy (SCIT) is cost-effective; however its economical burden can lead to non-adherence. We aimed to identify the reported reasons, patient’s personal or socio-demographic characteristics and SCIT-related factors associated with non-adherence to SCIT. Methods. This is a cross-sectional, observational study held in a Portuguese University Hospital. All records from patients starting SCIT in […]
Background. Allergen specific immunotherapy is the only causal therapy for respiratory allergies, and the only treatment that can modify the natural course of the disease. Information and education of patients is essential to successful treatment and, since the General Practitioner is the primary referral, a cooperation between him and the allergy specialists is crucial. We […]
In Europe more than 50% of asthmatic treated patients have a not well-controlled asthma.The present survey aims at investigating how different specialists approach asthmatic patients.A web anonymous questionnaire was randomly administered to 604 General Practitioners (GPs), 241 Pneumologists and 131 Allergists. It concerned: epidemiology, diagnostic workup, follow-up and risk factors, treatment and future risk. A […]
Review
The Component Resolved Diagnostic (CRD) approach has been developed when highly purified or recombinant allergen molecules have become available. These molecules are the allergenic proteins toward which the specific and clinically relevant IgE immune response is directed. So, the identification of protein families and cross-reactivity patterns of importance in allergy have been possible. The Italian […]
Correspondence
Hereditary angioedema (HEA) is a disease characterized by decreased levels or function of C1 esterase inhibitor (C1-INH). The symptoms of HEA in pediatric age group generally consist of recurrent episodes of soft tissue swelling. These symptoms can be transient, subtle, and varied in severity. Genitourinary system is rarely affected in this disease. Here, a three-year-old girl […]