Case Report
28 May 2014 / 17 April 2024 by almaware
In this report we describe un unusual case of exclusive allergic sensitization to furry animals, as a possible study model to speculate about different modalities of sensitization to allergens of common and less common mammalian species. A 27-year-old woman referred in our Allergological Centre for the occurrence of conjunctival and severe respiratory symptoms after contact […]
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Letter to the Editor
Background and Objective: Some studies hypothesize the existence of cross-reactivity between allergy to Cupressus sempervirens pollen and plant-derived foods.We aimed to assess whether this holds true.Methods: 72 patients monosensitized to cypress pollen were investigated for food allergy to peach, apple, tomato and Juniperius oxycedrus berry. Results: No patient had a history of clinical allergy or […]
Original Article
Background: Several comorbid conditions may contribute to worsening asthma symptoms, including nasal polyps (NPs). Cysteinyl leukotrienes (Cys-LTs) play a crucial role in asthma pathophysiology, and specific receptors for CysLTs are reported as upregulated in nasal polyp tissues. The aim of the present study was to assess the prevalence of nasal polyps in severe vs mild […]
Background: The clinical efficacy of Monophosphoryl lipid A-adjuvanted immunotherapy (MPLA-SCIT) is ascertained, but there are no data on its possible longlasting effect. We assessed in a real-life setting the persistence of the clinical effect five years after discontinuation. Methods: Patients with parietaria-induced respiratory allergy and fulfilling the criteria for immunotherapy prescription were evaluated at baseline, […]
The standardization of allergen extracts is of primary relevance to the clinical efficacy. Biological standardization procedures are widely used in the commercial production of vaccines. We tested, in grass-allergic patients, the potency of three different grass extracts for sublingual immunotherapy by means of skin prick tests. Specific IgE against Phl p 1, 2, 4, 5, […]
Background: Foods containing flaxseed proteins rich in polyunsaturated fatty acids are new on the market. Objectives: In a population of patients attending the allergology department, we evaluated the frequency of sensitization to flaxseed, characterized allergens and looked for modifications related to industrial processing. Methods: Natural, heated and extruded flaxseeds were tested using prick-in-prick tests (PIP […]
Congress
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Background: Epinephrine is the treatment of choice for acute food-allergic reactions but existing guidelines state that it should be prescribed uniquely to patients who already experienced at least one food-induced anaphylactic episode. Objective: We investigated whether in Italy epinephrine auto-injector is prescribed uniquely following the existing guidelines only, or is allergen-informed as well (i.e., based […]
Background: Allergy to crustacean shellfish is one of the most common IgE-mediated food allergies, and tropomyosin has been identified as the major allergen. However, not all subjects affected by this allergy are IgE-positive to tropomyosin. Aims: To evaluate whether sera of patients with shrimp allergy but negative for tropomyosin react to other allergen(s); and to […]
Review
Background: Specific oral tolerance induction (SOTI) is a new therapeutic approach in the treatment of persistent food allergy. Objective: The purpose of this article is to systematically review the literature in order to identify, appraise, and synthesize the evidence about SOTI efficacy and safety. Methods: A comprehensive search for citations was conducted on May 2, […]