Original Article
28 May 2014 / 17 April 2024 by almaware
Background: Epinephrine is the treatment of choice for acute food-allergic reactions but existing guidelines state that it should be prescribed uniquely to patients who already experienced at least one food-induced anaphylactic episode. Objective: We investigated whether in Italy epinephrine auto-injector is prescribed uniquely following the existing guidelines only, or is allergen-informed as well (i.e., based […]
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Background: Allergy to crustacean shellfish is one of the most common IgE-mediated food allergies, and tropomyosin has been identified as the major allergen. However, not all subjects affected by this allergy are IgE-positive to tropomyosin. Aims: To evaluate whether sera of patients with shrimp allergy but negative for tropomyosin react to other allergen(s); and to […]
Review
Background: Specific oral tolerance induction (SOTI) is a new therapeutic approach in the treatment of persistent food allergy. Objective: The purpose of this article is to systematically review the literature in order to identify, appraise, and synthesize the evidence about SOTI efficacy and safety. Methods: A comprehensive search for citations was conducted on May 2, […]
Case Report
25 May 2014 / 17 April 2024 by almaware
Skin testing is a reliable and safe way to diagnose IgE-mediated allergies, with rare side-effects. Two cases of systemic allergic reactions during skin testing to food allergens are hereby reported. A 28-year-old male reported allergic reactions, mild to moderate in severity, each time he tasted fish in the frame of his professional duties. During SPT […]
A woman, 68 yrs, developed an anaphylactic reaction after tasting a few pieces of gluten-free pasta. She was not celiac but was preparing a meal for her celiac nephew. The culprit pasta contained lupine flour and lupine proteins. Prick test with lupine extract was positive. ELISA and immunoblot analysis showed the presence of specific IgE […]
A case of anaphylaxis occurring during a general anesthesia is presented. The reaction was severe with bronchospasm and hypotension (grade 2 in the severity of per-operative anaphylactic shock). The responsibility of hydroxyzine, administered for premedication was suspected by intradermal testing with the molecule, which was twice positive at a 10-2 dilution of the commercial solution. […]
Letter to the Editor
The determination of specific IgE in patients with history of penicillins hypersensitivity is simple, safe and widely available. The positive and negative predictive values of this determination, however, are not yet established. In order to evaluate them, we performed specific IgE determination and diagnostic drug challenges in a group of 22 patients with a clear […]
Background: Natural rubber latex allergy is a condition at high risk of anaphylaxis during surgery. However, latex contains several protein allergens and not all of them may show the same clinical relevance. Objective: To investigate the clinical relevance of Hev b 8, the natural rubber latex profilin. Methods: Seven patients without a clinical history of […]
Background: Lipid transfer protein (LTP) is a widely cross-reacting plant pan-allergen, and sensitized patients may react to many foods. Although peanut allergy is frequently reported by LTP-allergic patients, the evidence of the presence of an allergen homologous to LTP in peanuts is limited. Objective: To assess the prevalence of peanut allergy in patients sensitized to […]
Rare allergens in indoor environment are insufficiently recognized. The sources are diverse: they include animal, namely acaride, insect and mammalian allergens or vegetable allergens. The prevalence of sensitization to rare allergens depends on geographical and climatological characteristics, on people’s habits and overall on dwelling specificities. Sensitizations to new rare allergens should be confirmed by documented […]