Review
28 May 2014 / 17 April 2024 by almaware
Since tropomyosin is cross reactive in many arthropods, it was assumed that this highly conserved protein could be responsible for cross reactions in house dust mite (HDM) allergic patients who experienced adverse reactions after crustacean and mollusc ingestion. Here we report two clinical cases where the role of tropomyosin is a matter of debate. In […]
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Case Report
Histamine is the main mediator of urticaria and H1-receptor antagonists represent the treatment of choice in all patients with chronic urticaria. Leukotriene receptor antagonists as montelukast have also been used in patients with chronic urticaria unresponsive to H1-antihistamines alone.We report a patient with chronic urticaria whose disease was paradoxically exacerbated by H1-antihistamines and montelukast, and […]
Original Article
Background: There is some evidence suggesting that factors other than autoantibodies to FceRI or IgE and histamine released from mast cells may play a role in skin autoreactivity that characterizes many patients with chronic urticaria (CU) and, possibly, in the pathogenesis of this disease. Objective: The effect of antihistamine treatment on autologous plasma skin test (APST) […]
The efficacy and safety of monomeric allergoid (Lofarma, Milan) have been demonstrated in adults but very few studies have examined it in children. This study therefore investigated the efficacy and safety of this sublingual immunotherapy (SLIT) at the dosage of 1000 AU five times a week without any up-dosing. Forty allergic children(17 M and 23 […]
Background: Carboxymethylcellulose (CMC) is used extensively in the pharmaceutical and food industries on account of its various properties. Anaphylactic reactions are rare. It has been reported principally after intra-articular infiltration of sustained-release corticosteroids containing CMC and, very rarely, after barium enema. Methods: A case of pre-lethal anaphylactic shock after barium enema was studied by prick-test, […]
Uncategorized
The subcutaneous modality of immunotherapy injections (SCIT) remained for several decades the only available administration route. SCIT is effective and safe, when properly prescribed and administered, but a remote risk of severe side effects is present (1), and the occurrence of technical errors is still not negligible (2). The problem of the risk/benefit ratio prompted […]
Omalizumab is an anti-IgE monoclonal antibody available since 2006 for the treatment of GINA step 4 asthma. We studied a 41-year old male who has been suffering from severe steroid-resistant asthma with severe co-morbidity and treated with Omalizumab. He was found to be non-responder to the treatment until the 48th week, starting from which we […]
In literature it has been described a high risk of systemic reaction after blood-sucking Dyptera bites, like mosquitoes and horsefly, in people sensitive to hymenoptera. A 51 year old man, allergic to hymenoptera venom and with a history of IV reaction after Mueller , who has been treated with Vespula sp. ITS for the last […]
Aim: to assess the accuracy and safety of a ready-to-use atopy patch test (HDM-Diallertest ®, DBV Technologies, Paris) in the diagnosis of sensitization to house-dust mite (HDM) allergens in children with or without atopic dermatitis. Patients and methods: prospective analysis of a systematic allergic work-up was carried out in 47 children, age 57.4+42 months (mean […]