Original Article
28 May 2014 / 17 April 2024 by almaware
Guidelines recognize the importance of achieving and maintaining asthma control: the treatment strategies now available allow the control of the great majority of patients with asthma but despite many efforts only 5% of patients achieve guideline-defined asthma control. The GAPP (The Global Asthma Physician and Patient survey) is a global quantitative survey with the aim […]
Read more »
Background: Cross-reactions between venoms may be responsible for multiple diagnostic positivities in hymenoptera allergy. There is limited data on the cross-reactivity between Vespula spp and Vespa crabro, which is an important cause of severe reactions in some parts of Europe. We studied by CAP-inhibition assays and immunoblotting the cross-reactivity between the two venoms. Methods: Sera […]
Review
Increased asthma severity is not only associated with enhanced recurrent hospitalisation and mortality but also with higher social costs. Most cases of asthma are atopic in nature, with the trigger for acute asthma attacks and chronic worsening of inflammation being allergens inducing an immune response through immunoglobulins of IgE class. Currently antiinflammatory treatments are effective […]
Case Report
In this report we describe un unusual case of exclusive allergic sensitization to furry animals, as a possible study model to speculate about different modalities of sensitization to allergens of common and less common mammalian species. A 27-year-old woman referred in our Allergological Centre for the occurrence of conjunctival and severe respiratory symptoms after contact […]
Letter to the Editor
Background and Objective: Some studies hypothesize the existence of cross-reactivity between allergy to Cupressus sempervirens pollen and plant-derived foods.We aimed to assess whether this holds true.Methods: 72 patients monosensitized to cypress pollen were investigated for food allergy to peach, apple, tomato and Juniperius oxycedrus berry. Results: No patient had a history of clinical allergy or […]
Background: Several comorbid conditions may contribute to worsening asthma symptoms, including nasal polyps (NPs). Cysteinyl leukotrienes (Cys-LTs) play a crucial role in asthma pathophysiology, and specific receptors for CysLTs are reported as upregulated in nasal polyp tissues. The aim of the present study was to assess the prevalence of nasal polyps in severe vs mild […]
Background: The clinical efficacy of Monophosphoryl lipid A-adjuvanted immunotherapy (MPLA-SCIT) is ascertained, but there are no data on its possible longlasting effect. We assessed in a real-life setting the persistence of the clinical effect five years after discontinuation. Methods: Patients with parietaria-induced respiratory allergy and fulfilling the criteria for immunotherapy prescription were evaluated at baseline, […]
The standardization of allergen extracts is of primary relevance to the clinical efficacy. Biological standardization procedures are widely used in the commercial production of vaccines. We tested, in grass-allergic patients, the potency of three different grass extracts for sublingual immunotherapy by means of skin prick tests. Specific IgE against Phl p 1, 2, 4, 5, […]
Background: Foods containing flaxseed proteins rich in polyunsaturated fatty acids are new on the market. Objectives: In a population of patients attending the allergology department, we evaluated the frequency of sensitization to flaxseed, characterized allergens and looked for modifications related to industrial processing. Methods: Natural, heated and extruded flaxseeds were tested using prick-in-prick tests (PIP […]
Congress
1§§#§§#bool1