Recommendations for the use of molecular diagnostics in the diagnosis of allergic diseases

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Authors Information

Full list of Authors: D. Villalta1,a,b danilo.villalta@aas5.sanita.fvg.it, E. Tonutti2,a, N. Bizzaro3,a, I. Brusca4,a,b, V. Sargentini5,a, R. Asero6,b, M.B. Bilò7,b, G. Manzotti8,b, F. Murzilli9,b, L. Cecchi10,b, A. Musarra11,b

1 Allergologia e Immunologia Clinica, Ospedale S. Maria degli Angeli, Pordenone, Italy
2 Immunopatologia e Allergologia, Azienda Ospedaliero-Universitaria, Udine, Italy
3 Laboratorio di Patologia Clinica, Ospedali di Tolmezzo, Gemona, San Daniele (UD), Italy
4 Laboratorio Analisi, Ospedale Buccheri-La Ferla, Palermo, Italy
5 Laboratorio Analisi, P.T.P, Nuovo Regina Margherita, Roma, Italy
6 Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy
7 UOC di Allergologia, Azienda Ospedaliera-Universitaria Ospedali Riuniti, Ancona, Italy
8 Ambulatorio di allergologia, Dipartimento Area Medica, Ospedale di Treviglio (BG), Italy
9 UOSD di Allergologia, Ospedale S.S. Filippo e Nicola, Avezzano (AQ), Italy
10 SOC Allergologia e Immunologia Clinica, USL Toscana Centro, Prato, Italy
11 Servizio di Allergologia, Casa della Salute di Scilla, Scilla (RC), Italy

Gruppo di Studio in Allergologia della Società Italiana di Patologia Clinica e Medicina di Laboratorio (GdS-ALL SIPMeL)
b Associazione Italiana degli Allergologi e Immunologi Territoriali e Ospedalieri (AAIITO)


Published online: 27 November 2017
Accepted: 6 September 2017
Received: 13 July 2017


The Study Group on Allergology of the Italian Society of Clinical Pathology and Laboratory Medicine (SIPMeL) and the Associazione Italiana degli Allergologi e Immunologi Territoriali e Ospedalieri (AAIITO) developed the present recommendations on the diagnosis of allergic diseases based on the use of molecular allergenic components, whose purpose is to provide the pathologists and the clinicians with information and algorithms enabling a proper use of this second-level diagnostics. Molecular diagnostics allows definition of the exact sensitiza-tion profile of the allergic patient. The methodology followed to develop these recommenda-tions included an initial phase of discussion between all the components to integrate the knowledge derived from scientific evidence, a revision of the recommendations made by Ital-ian and foreign experts, and the subsequent production of this document to be disseminated to all those who deal with allergy diagnostics.

allergy; molecular diagnostics; component resolved diagnostics; guidelines; specific IgE

Table of Content: Vol. 50 (No. 2) 2018 March

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