Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction
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Authors Information
1 Immunoallergology Department, Dona Estefânia Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal
2 Occupational Health Department, São José Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal
History
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Published online: 29 November 2017
Accepted: 2 October 2017
Received: 29 August 2017
SUMMARY
Anticonvulsants are among the drugs most commonly involved in cutaneous adverse drug reactions (CADRs). Eslicarbazepine is a new anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. We report the clinical case of a woman who developed a skin rash on day 10 of eslicarbazepine with further exacerbation with eosinophilia on day 2 of carbamazepine. Epicutaneous tests were positive with eslicarbazepine.