2.6
2023

Omalizumab treatment in patient with severe Asthma and Eosinophilic Granulomatosis with Polyangiitis. A case report

SUMMARY

Eosinophilic Granulomatosis with Polyangiitis (EGPA), formerly named Churg Strauss Syndrome, is a multisystem disorder characterized by chronic rhinosinusitis, asthma, and prominent peripheral blood eosinophilia; it is classified as a vasculitis of the small and medium sized arteries, although the vasculitis is often not clinically apparent in the initial phases of the disease. We present the case of a woman with EGPA who was frequently treated with high dose steroid therapy during hospital admission for refractory asthma. After December 2008, the date when we started Omalizumab, we observed a significative reduction of circulating eosinophils and IgE serum level, and the patient was no more ospitalized for respiratory failure or asthma attacks.

Table of Content: Vol. 46 (No. 6) 2014 November

European Annals of Allergy and Clinical Immunology ISSN 1764-1489 | © 2024