Cypress pollen allergy is responsible for two distinct phenotypes of allergic rhinitis different from other pollinosis
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Authors Information
1 Aix Marseille Univ, APHM, Espace Éthique Méditerranéen, UMR 7268 ADES / EFS / CNRS, CIC 9502, Clinique des bronches allergies et sommeil, Marseille, France
2 APHM, Clinique des bronches allergies et sommeil, Marseille, France
3 UMR INSERM 1067 / CNRS 7333, Marseille, France
4 Aix Marseille Univ, APHM, UMR CNRS 7333, CIC 9502, INSERM U1067, Clinique des bronches allergies et sommeil, Marseille, France
5 APHM, Pneumology Unit, Hôpital de la Timone, Marseille, France Study conducted in APHM, Clinique des Bronches, allergies et sommeil, Marseille France
History
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Published online: 10 January 2018
Accepted: 8 September 2017
Received: 11 July 2017
SUMMARY
Different phenotypes of allergic rhinitis have been identified based on the seasonality of the allergen involved. Within pollinosis, importance has to be paid to the responsible pollen species. Guidelines for clinical management are mostly based on studies performed in patients with grass pollen allergy. Only few data is available on tree pollen allergy and more specifically on cypress pollen allergy. We focused on the clinical and biological features of cypress pollen allergy to determine whether it is associated with a specific phenotype of allergic rhinitis or not. Our results suggest that cypress pollen can be responsible for two distinct phenotypes of rhinitis, both different from other pollinosis. In the most common phenotype, cypress pollen was not responsible for bronchial hyperresponsiveness or systemic inflammation. Close attention has to be paid to the allergen involved in allergic rhinitis. Different phenotypes leading to different pharmacological strategies may apply.
