An unusual case of positive sIgE to Galactose-alpha-1,3-galactose from South Italy

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Authors Information

1 Allergy Diseases Center Prof G. Bonsignore, Institute of Biomedicine and Molecular Immunology A. Monroy (IBIM), National Research Council (CNR), Palermo, Italy
2 Laboratorio di Entomologia e Controllo Vettori Ambientali, Istituto Zooprofilattico Sperimentale della Sicilia A. Mirri, Italy
3 C.Re.N.A. (Centro di Referenza Nazionale Anisakiasi), Istituto Zooprofilattico Sperimentale della Sicilia A. Mirri, Italy
4 Clinical Pathology, Allergy Unit, Buccheri La Ferla Hospital, Palermo, Italy


Published online: 10 January 2018
Accepted: 12 May 2017
Received: 26 February 2017


We report the case of a 38-year-old man who was bitten several times during his life by a tick. He didn’t report any previous history of anaphylaxis after the ingestion of red meat. The serum specific IgE showed positivity to alpha-Gal. The proximity of the bits didn’t increase the titer of IgE antibodies to alpha-gal. We could hypothesize that the frequency of the exposure to the tick Corresponding author bites and the amount of tick bites during his lifetime induced a sort of tolerance in this patient.

sIgE to alpha-Gal; delayed food anaphylaxis; tick bit; basophil activation test; hunter

Table of Content: Vol. 50 (No. 1) 2018 January

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