Chronic spontaneous urticaria: from the hunt for causes and pathogenesis to the identification of different endotypes
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Authors Information
1Allergology Clinic, Clinica San Carlo, Paderno Dugnano, Milan, Italy
2Department of Immunology Outpatient, UO General Medicine, Bolognini Hospital, ASST Bergamo Est, Seriate, Bergamo, Italy
History
Published: 27 July 2023
Accepted: 26 July 2023
Received: 30 March 2023
SUMMARY
The hunt for the causes and pathogenic mechanisms involved in chronic spontaneous urticaria (CSU) has engaged clinicians and scientists for decades. Although not all aspects of the disease are defined, our knowledge has now improved to the point that we can consider CSU as an umbrella clinical phenotype under which several different endotypes probably exist. The present article will briefly summarize the fascinating history of the progress in our knowledge of this disease.
