The crucial role of allergists in the clinical management and treatment of eosinophilic esophagitis
Show more: Authors information and Publication history
Authors Information
1Allergy Unit, Azienda Ospedaliera S. Giuseppe Moscati, Avellino, Italy
2SOD Allergy and Clinical Immunology, Prato-Pistoia, Italy
3Allergologist, BIOS Spa, Rome, Italy
4Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia, Italy
5First Department of Internal Medicine, Clinica Medica I, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy
6Allergology Unit, IRCCS San Martino Polyclinic Hospital, Genoa, Italy
7Immunology and Allergy Unit, S. Maria degli Angeli Hospital, Pordenone, Italy
8SSI Allergology Romagna Health Authority, Rimini Hospital, Rimini, Italy
9Clinic Immunology Unit, Policlinico Umberto I, Rome, Italy
10Allergy Unit, Department of Internal Medicine, University Hospital of Marche, Ancona, Italy
11Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy
History
Published: 09 May 2025
Accepted: 30 April 2025
Received: 19 February 2025
SUMMARY
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus affecting mainly young individuals with a high burden of comorbid atopic diseases and is associated with increased morbidity. Proton pump inhibitors (PPIs) is often the first line of treatment by inducing clinical remission in 30-50% of patients. Recently new drugs, such as budesonide orodispersible tablets and a monoclonal antibody targeting interleukin-4 and 13, have been found to be effective in clinical trials and approved to treat this condition.
A prompt diagnosis and correct management of these patients is of paramount importance to prevent fibrostenosis of the oesophagus and to improve the quality of life. The complex management of patients living with EoE requires the integrated cooperation of several specialists, including allergists, gastroenterologists, pathologists, dietitians, and psychologist.
