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Pru p 3 sublingual immunotherapy ultra-rush protocol is safe and clinically effective


A.L. Moura al-moura@hotmail.com1, C. Pereira1,2, F.S. Regateiro1,3, J. Azevedo1, A. Todo Bom1,4, I. Carrapatoso1

Show more: Authors information and Publication history

Doi
https://doi.org/10.23822/EurAnnACI.1764-1489.99

Summary
Introduction. Sublingual immunotherapy (SLIT) with Pru p 3 can prevent severe allergic reactions to LTP-containing foods but the standard initiation protocol is time-consuming. Aim. Establish the safety of a novel ultra-rush initiation protocol for SLIT with Pru p 3. Methods. Prospective study comparing the side effects of the standard vs novel ultra-rush initiation protocols of SLIT with Pru p 3 in patients with anaphylaxis to LTP. Results. Fifteen patients were included (standard initiation, 5; ultra-rush initiation, 10), 80% females. All patients had oropharyngeal pruritus during initiation, 80% with spontaneous recovery, but no other gastro-intestinal, respiratory, cutaneous or systemic side effects occurred in any patient of both groups. Conclusion. The novel ultra-rush protocol halved the build-up time without increasing side effects.

Key words
LTP syndrome; peach allergy; Pru p 3; sublingual immunotherapy; ultra-rush protocol


Cite this article as:
Moura A.L, Pereira C, Regateiro F.S, Azevedo J, Todo Bom A, Carrapatoso I. Pru p 3 sublingual immunotherapy ultra-rush protocol is safe and clinically effective Eur Ann Allergy Clin Immunol. 2019;51(5):206-212. doi:10.23822/EurAnnACI.1764-1489.99


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