2.6
2023

Hypersensitivity reactions to COVID-19 vaccines: a case of Eosinophilic pneumonia following Sinovac/CoronaVac vaccination

Show more: Authors information and Publication history
Authors Information

1Division of Allergy and Immunology, Department of Pulmonary Medicine, School of Medicine, Koç University, Istanbul, Turkey
2Department of Pulmonary Medicine, School of Medicine, Koç University, Istanbul, Turkey
3Department of Infectious Diseases, School of Medicine, Koç University, Istanbul, Turkey
4Department of Infectious Diseases, Koc University Hospital, Istanbul, Turkey
5Department of Pulmonary Medicine, Koç University Hospital, Istanbul, Turkey
6Department of Pathology, Koç University, School of Medicine, Istanbul, Turkey

History

Published: 11 February 2022
Accepted: 11 February 2022
Received: 03 June 2021

SUMMARY

Hypersensitivity reactions has been reported with COVID-19 vaccines. Acute eosinophilic pneumonia has not been reported yet after Sinovac/CoronaVac vaccine. A 73-year-old woman presented with maculopapular rash, cough and dyspnea following Sinovac/CoronaVac injection. The complete blood count (CBC) indicated eosinophilia and further evaluation of the eosinophilia with CT and bronchoscopy confirmed a diagnosis of acute eosinophilic pneumonia. After methylprednisolone therapy, her rash resolved with marked improvement of the dyspnea. She is still on treatment and on the follow up period, we plan to continue steroid treatment at least 3 months.

KEY WORDS
COVID-19; COVID-19 vaccines; Sinovac/CoronaVac; SARS-CoV-2; eosinophiles; eosinophilic pneumonia; rash.

Table of Content: Vol. 55 (No. 1) 2023 January

European Annals of Allergy and Clinical Immunology ISSN 1764-1489 | © 2024