Prospective study of consecutive patch testing in patients with contact dermatitis using an adapted Latin American baseline series
Paulo Eduardo Silva Belluco belluco@outlook.com1, Pedro Giavina-Bianchi2, Rosana Zabulon Feijó Belluco1, Maria Rita Carvalho Garbi Novaes1, Carmelia Matos Santiago Reis1Show more: Authors information and Publication history1College of Health Sciences, School of Medicine, Brasília, Brazil
2Division of Clinical Immunology and Allergy, University of Sao Paulo, Sao Paulo, Brazil
HistoryPublished: 09 March 2022
Accepted: 07 March 2022
Received: 09 December 2021
Doi10.23822/EurAnnACI.1764-1489.250Summary
Background. Contact dermatitis is characterized by pruritic skin lesions with high prevalence rates. Our objective is to describe the clinical and epidemiological characteristics of a population with suspected contact dermatitis who underwent to a patch testing using an adapted Latin American baseline series.
Methods. Observational, descriptive, analytical clinical study with prospective data collection was performed. 208 participants who underwent patch testing using an adapted Latin American baseline series containing 40 allergens were analyzed. The prevalence of contact allergies was compared with data from the literature. Pearson's chi-square test was used for qualitative variables. Quantitative variables were compared using the Mann-Whitney U test. The significance of the regression parameters was tested using the Wald statistical test.
Results. A total of 69.7% had one or more positive tests. Among those, 82.8% were women (OR 1.371; p = 0.398). The hands were the most commonly affected site at 43%. An occupational history was detected in 19.2%. The most common allergens were nickel sulfate (32.2%), sodium tetrachloropalladate (19.7%), fragrance mix I (15.4%), and methylisothiazolinone (13.5%). In multivariate logistic regression models, nickel was significantly related to female sex, as well as palladium. Fragrance mix I was related to a family history of allergy (p < 0.05). Methylisothiazolinone wasstatistically significantly related to face and hand lesions.
Conclusions. This study demonstrated a detailed profile of a population with suspected allergic contact dermatitis. Our patch test results, using an adapted Latin Americanbaseline series, represent a significant update of this important diagnostic tool.
Key wordsContact dermatitis; patch test; allergy; Latin American; COVID-19.
Cite this article as: Belluco PES, Giavina-Bianchi P, Belluco RZF, Novaes MRCG, Reis CMS. Prospective study of consecutive patch testing in patients with contact dermatitis using an adapted Latin American baseline series. Eur Ann Allergy Clin Immunol. 2023;55(5):235-242. doi: 10.23822/EurAnnACI.1764-1489.250.
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