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Contents »

The diverse roles of T cell subsets in asthma


F. S. Regateiro regateiro@gmail.com1,2,3, P. Botelho Alves1, A. L. Moura1, J. P. Azevedo2,4, D. T. Regateiro5

Show more: Authors information and Publication history

Doi
http://doi.org/10.23822/EurAnnACI.1764-1489.177

Summary
T cells are coordinators of the immune response and have been shown to play a central role in the pathophysiology of asthma. A good understanding of the T cells functions in asthma is important for therapeutic reasons, in particular for the choice of biological treatments in severe asthma. Although classically considered a Th2 disease, it is now clear that other types of T cells contribute for the pathophysiology and the heterogeneity of asthma. We here review how the different subsets of T cells are involved in the different phenotypes/endotypes of asthma and how this may influence the treatment of the disease.

Key words
Asthma; T cells; regulatory T cells; asthma endotypes; asthma biomarkers.

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