Urticaria and coronavirus infection: a lesson from SARS-CoV-2 pandemic
A. Allegra1,2, R. Asero r.asero@libero.it3, A. Giovannetti4, S. Isola2,5, S. Gangemi5Show more: Authors information and Publication history1Division of Haematology, Department of Human Pathology in Adulthood and Childhood "Gaetano Barresi", University of Messina, Italy
2COVID Centre AOU Policlinic G. Martino, Messina, Italy
3Clinic of Allergology, Clinica San Carlo, Paderno Dugnano, Milan, Italy
4Department of Translational and Precision Medicine, Sapienza University, Rome, Italy
5Department of Clinical and Experimental Medicine, School and Operative Unit of Allergy and Clinical Immunology, University of Messina, Messina, Italy
History:Published online: 09 October 2020
Accepted: 05 October 2020
Received: 18 June 2020
Doihttp://doi.org/10.23822/EurAnnACI.1764-1489.173SummaryUrticaria is a condition involving both skin and mucosal tissues characterized by the presence of wheals and/or angioedema. The acute form has been related to allergic reactions to drugs or foods, interaction with chemicals, or infections.
We reviewed the association of urticaria with coronavirus infections.
This review was carried out by the use of two search engines for published original articles, employing two key terms correlated to urticaria and viruses: "urticaria" and one term linked to each virus.
The research of the relationships between SARS-CoV-2 and urticaria produced 18 papers (including a total of 114 cases). Surprisingly, the search for cases of urticaria in patients with SARS-CoV or MERS produced no results.
We tried to interpret this discrepancy and attempted to analyze the possible pathogenesis of urticaria lesions in SARS-CoV-2.
Key wordsUrticaria; allergy; SARS-CoV-2; COVID19; MERS-CoV; SARS-CoV.
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