1Dipartimento di Medicina Sperimentale e Clinica, Universita degli Studi di Firenze, Firenze, Italy
2Unita Dipartimentale di Allergologia-Immunologia Clinica e Pneumologia, Fondazione Poliambulanza, Brescia, Italy
3SOD Immunoallergologia, AOU-Careggi, Firenze, Italy
Publication History: Published online: 12 April 2019
Accepted: 05 April 2019
Received: 19 March 2019
Atopy is the result of the influence of environmental factors on genetically predisposed individuals. Migration flows represent an interesting model to study the possible reciprocal roles of genes and environment. In this review the following issues influencing the development of allergic sensitization and/or atopic disorders in migrants will be rooted out: 1) ethnicity, genetic polymorphisms and risk of atopy; 2) double faceted effects of parasitic infestations; 3) biodiversity loss and industrial progress. Moreover, an extensive revision of the literature about the relationship between the migratory status and allergy development is provided.
