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European Annals of Allergy and Clinical Immunology ISSN 1764-1489

© 2024

Contents »

Fatal asthma after omalizumab and controller therapy discontinuation: a case report


C. Lombardi1, M. Cottini2, G. Passalacqua3 passalacqua@unige.it

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Doi
https://doi.org/10.23822/EurAnnACI.1764-1489.70

Summary
In this clinical case we report a fatal asthma episode in a 28-year old female, who was sensitized to pollens and mould, and with episodes of near-fatal asthma. She was successfully treated with omalizumab, that was discontinued after 5 years. After that, the patient also discontinued controller medications. In 2015, 3 years after omalizumab discontinuation, she had a fatal asthma attack, with respiratory failure and needing mechanical ventilation. This case report suggests that omalizumab treatment should not be discontinued in near-fatal asthma cases P>

Key words
fatal asthma; omalizumab; alternaria