The clinical and laboratory findings of infants with atopic dermatitis during diagnosis and follow-up
A. Chousein
1, H. Duman Senol
dumanhandan@yahoo.com2, E. Ece Özdoğru
2, S. Eren Akarcan
2, T. Tuncel
3Show more: Authors information and Publication history1Department of Pediatrics, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey
2Department of Pediatric Allergy and Immunology, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey
3Division of Pediatric Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Izmir Katip Celebi University, Izmir, Turkey
HistoryPublished: 13 January 2023
Accepted: 09 January 2023
Received: 14 September 2022
Doi10.23822/EurAnnACI.1764-1489.281SummaryObjective. The aim of this study is to investigate the relationship between the clinical and laboratory findings of children aged 0-2 years with atopic dermatitis at the time of admission and prognosis during follow-up.
Materials and Methods. The study was conducted in İzmir Health Sciences University, Tepecik Training and Research Hospital. The clinical and laboratory data of patients between January 2014 and December 2019 were scanned from the patient records and the hospital data system.
Results. 102 patients with a median age of 8(9) (min 2- max 24) months were included in the study. The median age of onset of the symptoms was 3(5) (min 1-max 21) months. The patients most frequently (85.2%) presented with eczema and lesions were most common (60.7%) in the extremities. Most of the patients (56.9%) had mild dermatitis. In the 6
th month, 26.5% who continued follow-up had clinical improvement. Food allergy was present in 33.3% of the patients. The most common food allergen was egg (52.9%). Food allergy was associated with the severity of atopic dermatitis (p = 0.033), and the symptoms started earlier (p = 0.002). There is no relationship between the severity of atopic dermatitis and gender, family history, presence of additional atopic disease, response to treatment, total IgE and eosinophil count (p > 0.05); however, it was determined that the symptoms started earlier in patients with moderate/severe atopic dermatitis (p = 0.002).
Conclusions. Food allergy is more common in the early-onset and moderate/severe atopic dermatitis. Accurate diagnosis of food allergy is necessary to increase the success of treatment and to prevent unnecessary diets.
Key wordsAtopic dermatitis; food allergy; infant; prognosis.
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