Does maternal diet during pregnancy influence clinical and laboratory characteristics of infantile-onset atopic dermatitis?

D. Milewska-Wróbel, A. Lis-Œwiêty annadlis@neostrada.pl

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Doi
http://doi.org/10.23822/EurAnnACI.1764-1489.170

Summary
Background. Prenatal environmental factors are suggested to be implicated in the dramatic increase in atopic dermatitis (AD) in recent years. The aim of this study was to investigate the possible associations between pregnant woman's diet and clinical and laboratory variables of AD in offsprings. Methods. A cross-sectional study was performed in children 3-36 months of age with infantile-onset AD. Maternal dietary habits during pregnancy were evaluated in terms of the usual intake of dairy foods, eggs, red meat and poultry, fish, fruits and vegetables. Results. One hundred pairs of mothers and their children with AD were included. A higher serum total IgE and peripheral eosinophila in children were associated with a lower maternal egg intake during pregnancy. Except for a strong trend toward significance of correlation between fish consumption and the lack of atopic multimorbidity, no relationships were revealed between clinical variables of child's AD (the age of onset of AD, its severity, atopic multimorbidity) and the mother's dietary habit. Conclusions. Our preliminary findings suggest that maternal egg intake during pregnancy might be a factor influencing laboratory markers of atopy in offsprings. Prospective cohort studies are needed to confirm and clarify this relationship.

Key words
Atopic dermatitis; diet; pregnancy; primary prevention; peripheral eosinophila; serum total IgE.

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