1 Allergy Diseases Center Prof G. Bonsignore, Institute of Biomedicine and Molecular Immunology A. Monroy (IBIM), National Research Council (CNR), Palermo, Italy
2 Laboratorio di Entomologia e Controllo Vettori Ambientali, Istituto Zooprofilattico Sperimentale della Sicilia A. Mirri, Italy
3 C.Re.N.A. (Centro di Referenza Nazionale Anisakiasi), Istituto Zooprofilattico Sperimentale della Sicilia A. Mirri, Italy
4 Clinical Pathology, Allergy Unit, Buccheri La Ferla Hospital, Palermo, Italy
Publication History:
Published online: 10 January 2018
Accepted: 12 May 2017
Received: 26 February 2017
We report the case of a 38-year-old man who was bitten several times during his life by a tick. He didn't report any previous history of anaphylaxis after the ingestion of red meat. The serum specific IgE showed positivity to alpha-Gal. The proximity of the bits didn't increase the titer of IgE antibodies to alpha-gal. We could hypothesize that the frequency of the exposure to the tick Corresponding author bites and the amount of tick bites during his lifetime induced a sort of tolerance in this patient.
sIgE to alpha-Gal; delayed food anaphylaxis; tick bit; basophil activation test; hunter