Omalizumab for refractory chronic spontaneous urticaria during concurrent immunomodulatory therapy for multiple sclerosis
N. Syrigos1, D. Grapsa2 dimgrap@yahoo.gr, E. Syrigou1Show more: Authors information and Publication history1 Allergy Department, "Sotiria" General Hospital, Athens, Greece
2 3
rd Department of Medicine, "Sotiria" General Hospital, Medical School, University of Athens, Athens, Greece
Publication History:
Published online: 2 November 2017
Accepted: 11 April 2017
Received: 24 March 2017
Doihttps://doi.org/10.23822/EurAnnACI.1764-1489.20 SummaryData derived from previous clinical trials and real-life studies have shown that omalizumab may represent an effective third-line treatment option for patients with chronic spontaneous urticaria (CSU) refractory to standard antihistamine treatment. Nevertheless, the safety and efficacy of omalizumab treatment for CSU, when administered concurrently with other immunomodulatory agents remains largely unknown. We herein present the case of a female patient with relapsing-remitting multiple sclerosis (RRMS), under treatment with interferon beta-1a, azathioprine and gabapentin, who was successfully treated with omalizumab for refractory CSU. To the best of our knowledge, this is the first reported case attesting to the safety and efficacy of omalizumab for CSU when administered concurrently with other immunomodulatory agents.
Key words
angioedema; antihistamines; chronic spontaneous urticaria; omalizumab; multiple sclerosis
FULL TEXTCite this article as:
Syrigos N et al. Omalizumab for refractory chronic spontaneous urticaria during concurrent immunomodulatory therapy for multiple sclerosis. Eur Ann Allergy Clin Immunol. 2017;49(6):286-287. doi:10.23822/EurAnnACI.1764-1489.20