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European Annals of Allergy and Clinical Immunology ISSN 1764-1489

© 2024

Table of Contents »

Human insulin allergy: four case reports


A.Teixeira Rodrigues, L.F. Chiaverini Ensina, L. Sabino Garro, L. Kase Tanno, P.Giavina-Bianchi, A. Abilio Motta

Insulin allergy was not uncommon in the past, but has lowered with the introduction of human recombinant insulin. Human recombinant insulin allergy is a rare condition, now reported in less than 1% of treated patients. However, it is a serious condition that requires an immediate allergological work-up. In this study, we describe 4 cases of IgEmediated reaction to human recombinant insulin, emphasizing some practical aspects in diagnosis and treatment.

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