Allergy Unit, Instituto and Hospital CUF, Porto, Portugal2
Center for Health Technology and Services Research (CINTESIS), School of Medicine, University of Porto, Porto, Portugal3
Medicina, EDucação, Investigação, Desenvolvimento e Avaliação (MEDIDA), Porto, Portugal4
Department of Community Medicine, Information and Health Decision Sciences (MEDCIDS), School of Medicine, University of Porto, Porto, Portugal5
Porto Health School, Polytechnic Institute of Porto, Porto, PortugalHistory
Published: 22 December 2020
Accepted: 25 November 2020
Received: 17 July 2020
To assess the association between the number of allergen sensitizations and lung function variables in individuals with airway symptoms.
Retrospective study with all individuals who performed lung function and skin-prick tests at CUF-Porto (01/2011-06/2016). Six allergen groups were considered. % predicted Pre-Bronchodilator test (BD) and % change after BD were analysed for spirometry and plethysmography parameters.
A total of 1293 individuals were included, 54% (n = 698) adults and 69% (n = 891) with sensitization to ≥ 1 allergen group. % FEV1 was significantly higher and % change in FEV1 significantly lower in non-sensitized individuals. % sRaw was higher in polysensitized (
The presence of allergen sensitizations was significantly associated with worse key lung function parameters.
Allergen; sensitization; lung function; airways; skin prick test.